The first organophosphate intoxication cases that were published in Archives of Toxicology
were caused by parathion (E605), and a high acute toxicity of this chemical was noted, at a …

Abstract The uncharged 3-hydroxy-2-pyridine aldoximes with protonatable tertiary amines
are studied as antidotes in toxic organophosphates (OP) poisoning. Due to some of their …

Sets of 346 herbicides in use and 163 no longer in use were collected from open access
online sources and compared in silico with cholinesterases inhibitors (ChI) and drugs in …

As butyrylcholinesterase (BChE) plays a role in the progression of symptoms and
pathophysiology of Alzheimer's disease (AD), selective inhibition of BChE over …

The cholinergic system, relying on the neurotransmitter acetylcholine (ACh), plays a
significant role in muscle contraction, cognition, and autonomic nervous system regulation …

The toxicity of eight polybrominated diphenyl ethers (PBDEs) congeners detected in
environmental and biological samples (BDE-28,-47,-99,-100,-153,-154,-183, and-209) was …

Oxime reactivators of acetylcholinesterase (AChE) are used as causal antidotes for intended
and unintended poisoning by organophosphate nerve agents and pesticides. Despite all …

New furan, thiophene, and triazole oximes were synthesized through several-step reaction
paths to investigate their potential for the development of central nervous systems (CNS) …

Organophosphate (OP) poisoning, both accidental and with suicidal intent, is a global
medical challenge. While the primary toxicity of these pesticides is based on the inhibition of …

Praćenjem učinka odabranih imidazolijevih i kloriranih bispiridinijevih oksima utvrđeno je da
uzrokuju citotoksičnost i aktiviraju različite mehanizme ili tipove stanične smrti. Kako bismo …