Retinal photoreceptor cells contain a specialized outer segment (OS) compartment that
functions in the capture of light and its conversion into electrical signals in a process known …

To serve vision, vertebrate rod and cone photoreceptors must detect photons, convert the
light stimuli into cellular signals, and then convey the encoded information to downstream …

Cilia are hair-like projections found on almost all cells in the human body. Originally
believed to function merely in motility, the function of solitary non-motile (primary) cilia was …

Peripherin/rds is an integral membrane glycoprotein, mainly located in the rod and cone
outer segments. The relevance of this protein to photoreceptor outer segment morphology …

For over 30 years, photoreceptors have been an outstanding model system for elucidating
basic principles in sensory transduction and G protein signaling. Recently, photoreceptors …

Vision is the most fundamental of our senses initiated when photons are absorbed by the
rod and cone photoreceptor neurons of the retina. At the distal end of each photoreceptor …

The primary cilium is a highly conserved organelle housing specialized molecules
responsible for receiving and processing extracellular signals. A recently discovered …

Mammalian peripherin-2 (PRPH2) and rod outer segment membrane protein 1 (ROM1) are
retina-specific tetraspanins that partake in the constant renewal of stacked membrane discs …

Abstract Peripherin 2 (PRPH2), also known as RDS (retinal degeneration slow) is a
photoreceptor specific glycoprotein which is essential for normal photoreceptor health and …

Rhodopsin is a key molecular constituent of photoreceptor cells, yet understanding of how it
regulates photoreceptor membrane trafficking and biogenesis of light-sensing organelles …