The voltage-dependent anion channel (VDAC), the most abundant protein in the outer
mitochondrial membrane, is responsible for the transport of all ions and metabolites into and …

Interactions between membrane proteins (MPs) and lipid bilayers are critical for many
cellular functions. In the Rosetta molecular modeling suite, the implicit membrane energy …

Highlights•Structural information is required to fully understand the molecular basis of
transporter function.•Resolved atomic structures of transporters must put into context with …

There have been several studies suggesting that protein structures solved by NMR
spectroscopy and X‐ray crystallography show significant differences. To understand the …

Numerous studies have investigated the differences and similarities between protein
structures determined by solution NMR spectroscopy and those determined by X‐ray …

SLC6 neurotransmitter transporters facilitate the Na+-and Cl−-dependent uptake of amino
acids and amino acid derivatives into cells. Disrupting transport leads to a range of …

The SASPAR program for calculation of SAXS of proteins in solution uses trajectories of
molecular dynamics (MD) and an explicit solvent model. The program allows one to take into …

Membrane proteins (MPs) exist in complex and diverse membrane environments in which
they function. Cellular membranes adopt different geometries and cover a variety of different …

The application of coarse-grained computational models to the study of physical systems
has explodedin recent years, in part due to the relative simplicity of such models compared …

Although the amount of experimental and theoretical protein studies have grown
exponentially in recent years, we still do not have enough knowledge about the folding …