[HTML][HTML] Non-vasogenic cystoid maculopathies

A Gaudric, I Audo, C Vignal, A Couturier… - Progress in Retinal and …, 2022 - Elsevier
Besides cystoid macular edema due to a blood-retinal barrier breakdown, another type of
macular cystoid spaces referred to as non-vasogenic cystoid maculopathies (NVCM) may be …

The Genetic Determinants of Axial Length: From Microphthalmia to High Myopia in Childhood

D Jackson, M Moosajee - Annual Review of Genomics and …, 2023 - annualreviews.org
The axial length of the eye is critical for normal visual function by enabling light to precisely
focus on the retina. The mean axial length of the adult human eye is 23.5 mm, but the …

[HTML][HTML] Fullerol rescues the light-induced retinal damage by modulating Müller glia cell fate

Z Cha, Z Yin, A Luodan, L Ge, J Yang, X Huang, H Gao… - Redox Biology, 2023 - Elsevier
Excessive light exposure can damage photoreceptors and lead to blindness. Oxidative
stress serves a key role in photo-induced retinal damage. Free radical scavengers have …

Direct neuronal reprogramming by temporal identity factors

C Boudreau-Pinsonneault, LA David… - Proceedings of the …, 2023 - National Acad Sciences
Temporal identity factors are sufficient to reprogram developmental competence of neural
progenitors and shift cell fate output, but whether they can also reprogram the identity of …

Treatment of nanophthalmos cataracts: surgery and complications

MY He, JR Feng, L Zhang - Seminars in Ophthalmology, 2022 - Taylor & Francis
Purpose Cataract surgery in patients with nanophthalmos is complicated for
ophthalmologists to perform. Due to the unique ocular anatomy, there is a high incidence of …

Insights Into Myopia from Mouse Models

R Mazade, T Palumaa, MT Pardue - Annual Review of Vision …, 2024 - annualreviews.org
Animal models are critical for understanding the initiation and progression of myopia, a
refractive condition that causes blurred distance vision. The prevalence of myopia is rapidly …

A multiethnic genome-wide analysis of 19,420 individuals identifies novel loci associated with axial length and shared genetic influences with refractive error and …

C Jiang, RB Melles, J Yin, Q Fan, X Guo… - Frontiers in …, 2023 - frontiersin.org
Introduction: Long axial length (AL) is a risk factor for myopia. Although family studies
indicate that AL has an important genetic component with heritability estimates up to 0.94 …

IC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice

H Yuan, S Chen, MR Duncan, JP de Rivero Vaccari… - Angiogenesis, 2024 - Springer
Background Retinopathy of prematurity (ROP), which often presents with bronchopulmonary
dysplasia (BPD), is among the most common morbidities affecting extremely premature …

Integrative transcriptome and proteome analyses elucidate the mechanism of lens-induced myopia in mice

S Ji, L Ye, J Yuan, Q Feng, J Dai - … Ophthalmology & Visual …, 2023 - iovs.arvojournals.org
Purpose: The purpose of this study was to investigate the underlying molecular mechanism
of lens-induced myopia (LIM) through transcriptome and proteome analyses with a modified …

Clinical features of patients with mutations in genes for nanophthalmos

X Li, H Xiao, Y Su, X Xiao, S Li, S Lin, L Fang… - British Journal of …, 2024 - bjo.bmj.com
Background/Aims To distinguish the clinical feature of nanophthalmos (NNO) caused by
mutations in protease serine 56 (PRSS56), membrane-type frizzled-related protein (MFRP) …