Effectively delivering therapeutics for treating brain tumors is hindered by the physical and
biological barriers in the brain. Even with the compromised blood–brain barrier and highly …

The objective of this work was to develop self-forming doxorubicin-loaded polymeric depots
as an injectable drug delivery system for liver cancer chemotherapy and studied the release …

Hydrocephalus is a neurological disease caused by an unusually high level of
cerebrospinal fluid (CSF), which can be relieved by external ventricular drainage (EVD) …

Purpose SN-38, a potent chemotherapeutic drug, has not been used clinically because of its
severe side effects and poor solubility. In this work, we aimed to evaluate the effect of dose …

We investigate antitumor efficacy and 2D and 3D intratumoral distribution of 7-ethyl-10-
hydroxycamptothecin (SN-38) from polymeric depots inside U-87MG xenograft tumor model …

Malignant glioma (MG) is extremely aggressive and highly resistant to chemotherapeutic
agents. Using electrospraying, the potent chemotherapeutic agent 7-ethyl-10 …

In this work, paclitaxel-encapsulated polymeric depots were prepared and characterized as
drug delivery system for cancer chemotherapy against hepatocellular carcinoma. Effects of …

A sustained release that can be controllable is an ultimate goal for the delivery of drugs in
drug delivery systems including in situ depots. However, one of the major persistent …

Quantitative detection of two different forms of SN‐38 in biological samples is, currently,
cumbersome and difficult. A revisit to the mechanism of supramolecular complexation …

Using polymer and lipid-based drug delivery techniques, the primary objective is to enhance
bioavailability, solubility, and dissolution. Studies have proven therapeutic effectiveness …