This comprehensive State of the Art review summarizes the current published knowledge
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …

The ventilation of the lung ranges between 1,000 and 21,000 liters per 24 hours in humans
depending on body size and physical activity. This exposes the extensive epithelial surface …

Cystic fibrosis is an autosomal recessive disease caused by mutations of a gene located on
the long arm of chromosome 7.1 The gene product is the 1480-amino-acid cystic fibrosis …

Background. Cystic fibrosis is characterized by abnormal electrolyte transport across the
epithelia of the airways. In particular, there is excessive sodium absorption and de.. cient …

CYSTIC fibrosis (CF) is a lethal inherited disorder affecting about 1 in 2,000 Caucasians.
The major cause of morbidity is permanent lung damage resulting from ion transport …

In patients with cystic fibrosis (CF), dehydration of airway secretions leads to a decrease in
mucociliary clearance (MCC). We examined the acute effect of MCC of a single …

Objective The aim of the present study was to investigate the efficacy of two frequently used
physiotherapies (PTs) for the removal of bronchial secretions in cystic fibrosis (CF) lung …

Cystic fibrosis is the most common life-shortening autosomal recessive disease of white
persons in the United States, affecting approximately 30,000 individuals. The median 1992 …

Background Long-term benefits of newborn screening (NBS) for cystic fibrosis (CF) have
been established with respect to nutritional status, but effects on pulmonary health remain …

Mucociliary clearance (MCC), the process in which airway mucus together with substances
trapped within are moved out of the lungs, is an important defence mechanism of the human …