The forced swim test (FST) is a behavioral test in rodents which was developed in 1978 by
Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant …

During the last decade, the questions on the functionality of adult neurogenesis have
changed their emphasis from if to how the adult-born neurons participate in a variety of …

Mephedrone (MMC) is a relatively new recreational drug that has rapidly increased in
popularity in recent years. This study explored the characteristics of intravenous MMC self …

Selective serotonin reuptake inhibitor (SSRI) antidepressants are the mainstay treatment for
the 10–20% of pregnant and postpartum women who suffer major depression, but the effects …

Environmental factors play a significant role in well‐being of laboratory animals. Regulations
and guidelines recommend, if not require, that stressors such as bright lighting, smells, and …

ABSTRACT Mephedrone (4‐methylmethcathinone) is a novel recreational drug that has
rapidly increased in popularity in recent years. Users report mephedrone as having the …

Modelling of complex psychiatric disorders, eg, depression and schizophrenia, in animals is
a major challenge, since they are characterized by certain disturbances in functions that are …

Objective This study examined the long-term effects of fluoxetine administered to juvenile
rhesus monkeys who, as young adults, were imaged with positron emission tomography for …

Depression is a serious public health concern. Many patients are not effectively treated, but
in children and adolescents this problem is compounded by limited pharmaceutical options …

Infants born to women with depressive symptoms are at higher risk for insecure attachment
and behavioral problems. Thus current medical practice is to continue psychotropic …