Integrin conformational dynamics and mechanotransduction

R Kolasangiani, TC Bidone, MA Schwartz - Cells, 2022 - mdpi.com
The function of the integrin family of receptors as central mediators of cell-extracellular
matrix (ECM) and cell–cell adhesion requires a remarkable convergence of interactions and …

Hydrogels based on chitosan in tissue regeneration: How do they work? A mini review

J Jiao, J Huang, Z Zhang - Journal of Applied Polymer Science, 2019 - Wiley Online Library
The repair of tissue defects after injury is of significant clinical and research importance. A
variety of chitosan‐based hydrogels have been investigated and applied to address this …

Adhesive ligand tether length affects the size and length of focal adhesions and influences cell spreading and attachment

SJ Attwood, E Cortes, AWM Haining, B Robinson… - Scientific reports, 2016 - nature.com
Cells are known to respond to physical cues from their microenvironment such as matrix
rigidity. Discrete adhesive ligands within flexible strands of fibronectin connect cell surface …

Molecular force sensors: from fundamental concepts toward applications in cell biology

M Goktas, KG Blank - Advanced Materials Interfaces, 2017 - Wiley Online Library
Mechanical signals are central for the regulation of developmental, physiological, and
pathological processes within biological systems. Force transduction across the cell …

[PDF][PDF] From single molecules to bulk materials: tuning the viscoelastic properties of coiled coil cross-linked hydrogels

I Tunn - 2020 - pure.mpg.de
The development of bioinspired self-assembling materials, such as hydrogels, with
promising applications in cell culture, tissue engineering and drug delivery is a current focus …

Double-stranded DNA force sensors to study the molecular level forces required to activate signaling pathways

Y Kim, KA Kim, BC Kim - Journal of the Korean Physical Society, 2021 - Springer
Single-molecule force measurement techniques provide unique opportunities to investigate
simple molecular interactions and complicated force-induced cell responses. This has …

Single-molecule Force Microscopy: A Powerful Tool for Studying the Mechanical Properties of Cell Membranes

Y Shi, M Cai, H Wang - Current Analytical Chemistry, 2022 - ingentaconnect.com
Background: Cell membrane is a physical barrier for cells, as well as an important structure
with complex functions in cell activities. The cell membrane can not only receive external …

Coiled coils as molecular force sensors for the extracellular matrix

M Göktas - 2019 - pure.mpg.de
Kraft spielt eine fundamentale Rolle bei der Regulation von biologischen Prozessen. Zellen
messen mechanische Eigenschaften der extrazellulären Matrix und benutzen diese …