Lutein and zeaxanthin belong to the xanthophyll family of carotenoids, which are pigments
produced by plants. Structurally, they are very similar, differing only slightly in the …

Oxidative stress is an important pathomechanism found in numerous ocular degenerative
diseases. To provide a better understanding of the mechanism and treatment of …

Oxidative stress plays a crucial role in aging-related eye diseases, including age-related
macular degeneration (AMD), cataracts, and glaucoma. With age, antioxidant reparative …

Background Age‐related macular degeneration (AMD) is a degenerative condition of the
back of the eye that occurs in people over the age of 50 years. Antioxidants may prevent …

Age-related macular degeneration (AMD) remains a leading cause of modifiable vision loss
in older adults. Chronic oxidative injury and compromised antioxidant defenses represent …

Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically
heterogeneous diseases characterized by the progressive degeneration of the retina …

Aging is a multi-faceted process caused by the accumulation of cellular damage over time,
associated with a gradual reduction of physiological activities in cells and organs. This …

The aim of this paper is to summarize all available evidence from systematic reviews,
randomized controlled trials (RCTs) and comparative nonrandomized studies (NRS) on the …

Epigenetics focuses on DNA methylation, histone modification, chromatin remodeling,
noncoding RNAs, and other gene regulation mechanisms beyond the DNA sequence. In the …

Given the expanding elderly population in the United States and the world, it is important to
understand the processes underlying both natural and pathological age-related changes in …