Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines

M Filippi, P Preziosa, BL Banwell, F Barkhof… - Brain, 2019 - academic.oup.com
MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

The current role of MRI in differentiating multiple sclerosis from its imaging mimics

R Geraldes, O Ciccarelli, F Barkhof… - Nature Reviews …, 2018 - nature.com
MRI red flags proposed over a decade ago by the European Magnetic Resonance Network
in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS) …

[HTML][HTML] Acute unilateral vestibulopathy/vestibular neuritis: Diagnostic criteria

M Strupp, A Bisdorff, J Furman… - Journal of …, 2022 - content.iospress.com
This paper describes the diagnostic criteria for Acute Unilateral Vestibulopathy (AUVP), a
synonym for vestibular neuritis, as defined by the Committee for the Classification of …

Paramagnetic rim lesions are specific to multiple sclerosis: an international multicenter 3T MRI study

P Maggi, P Sati, G Nair, ICM Cortese… - Annals of …, 2020 - Wiley Online Library
In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on
magnetic resonance imaging by their paramagnetic rims, and increasing evidence supports …

Susac syndrome: challenges in the diagnosis and treatment

M Marrodan, MP Fiol, J Correale - Brain, 2022 - academic.oup.com
Susac syndrome is a disorder thought to be mediated by an autoimmune response towards
endothelial cells, leading to a characteristic clinical triad of encephalopathy, visual …

[HTML][HTML] CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome

CC Gross, C Meyer, U Bhatia, L Yshii, I Kleffner… - Nature …, 2019 - nature.com
Neuroinflammation is often associated with blood-brain-barrier dysfunction, which
contributes to neurological tissue damage. Here, we reveal the pathophysiology of Susac …

[HTML][HTML] The CD8 T cell-Epstein-Barr virus-B cell trialogue: a central issue in multiple sclerosis pathogenesis

C Veroni, F Aloisi - Frontiers in immunology, 2021 - frontiersin.org
The cause and the pathogenic mechanisms leading to multiple sclerosis (MS), a chronic
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …

Guidelines for treatment of Susac syndrome–An update

RM Rennebohm, N Asdaghi… - … journal of stroke, 2020 - journals.sagepub.com
Susac syndrome is an immune-mediated, pauci-inflammatory, ischemia-producing,
occlusive microvascular endotheliopathy/basement membranopathy that affects the brain …

What is the potential of paramagnetic rim lesions as diagnostic indicators in multiple sclerosis?

MS Martire, L Moiola, MA Rocca, M Filippi… - Expert review of …, 2022 - Taylor & Francis
Introduction In multiple sclerosis (MS), paramagnetic rim lesions (PRLs) on MRI identify a
subset of chronic active lesions (CALs), which have been linked through clinical and …

Susac syndrome: a scoping review

C David, K Sacré, MC Henri-Feugeas, I Klein… - Autoimmunity …, 2022 - Elsevier
Susac syndrome is a rare disease characterized by an inflammatory microangiopathy limited
to the brain, eye, and ear vessels. It mainly affects young women. Although the …