Advances in biosynthesis, regulation, and metabolic engineering of plant specialized terpenoids

DA Nagegowda, P Gupta - Plant Science, 2020 - Elsevier
Plant specialized terpenoids are natural products that have no obvious role in growth and
development, but play many important functional roles to improve the plant's overall fitness …

Plant terpene specialized metabolism: complex networks or simple linear pathways?

ER Lanier, TB Andersen, B Hamberger - The Plant Journal, 2023 - Wiley Online Library
From the perspectives of pathway evolution, discovery and engineering of plant specialized
metabolism, the nature of the biosynthetic routes represents a critical aspect. Classical …

Cannabis glandular trichomes alter morphology and metabolite content during flower maturation

SJ Livingston, TD Quilichini, JK Booth… - The Plant …, 2020 - Wiley Online Library
The cannabis leaf is iconic, but it is the flowers of cannabis that are consumed for the
psychoactive and medicinal effects of their specialized metabolites. Cannabinoid …

Microbial cell factories for the production of terpenoid flavor and fragrance compounds

FM Schempp, L Drummond, M Buchhaupt… - Journal of agricultural …, 2017 - ACS Publications
Terpenoid flavor and fragrance compounds are of high interest to the aroma industry.
Microbial production offers an alternative sustainable access to the desired terpenoids …

Establishing Komagataella phaffii as a Cell Factory for Efficient Production of Sesquiterpenoid α-Santalene

Y Zuo, F Xiao, J Gao, C Ye, L Jiang… - Journal of Agricultural …, 2022 - ACS Publications
Santalene, a major component of the sandalwood essential oil, is a typical representative of
sesquiterpenes and has important applications in medicine, food, flavors, and other fields …

[HTML][HTML] Plant cytochrome P450 plasticity and evolution

CC Hansen, DR Nelson, BL Møller, D Werck-Reichhart - Molecular Plant, 2021 - cell.com
The superfamily of cytochrome P450 (CYP) enzymes plays key roles in plant evolution and
metabolic diversification. This review provides a status on the CYP landscape within green …

[HTML][HTML] Rationally engineering santalene synthase to readjust the component ratio of sandalwood oil

W Zha, F Zhang, J Shao, X Ma, J Zhu, P Sun… - Nature …, 2022 - nature.com
Plant essential oils (PEOs) are widely used in cosmetic and nutraceutical industries. The
component ratios of PEOs determine their qualities. Controlling the component ratios is …

The beauty of biocatalysis: sustainable synthesis of ingredients in cosmetics

RS Heath, RE Ruscoe, NJ Turner - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 2015 up to July 2021 The market for cosmetics is consumer driven and the desire
for green, sustainable and natural ingredients is increasing. The use of isolated enzymes …

[HTML][HTML] Plant metabolic gene clusters: evolution, organization, and their applications in synthetic biology

R Bharadwaj, SR Kumar, A Sharma… - Frontiers in Plant …, 2021 - frontiersin.org
Plants are a remarkable source of high-value specialized metabolites having significant
physiological and ecological functions. Genes responsible for synthesizing specialized …

Oxidation and cyclization of casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L.

D Luo, R Callari, B Hamberger… - Proceedings of the …, 2016 - National Acad Sciences
The seed oil of Euphorbia lathyris L. contains a series of macrocyclic diterpenoids known as
Euphorbia factors. They are the current industrial source of ingenol mebutate, which is …