Hemolysis is a pathological feature of several diseases of diverse etiology such as
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …

Stroke is a devastating disease that occurs when a blood vessel in the brain is either
blocked or ruptured, consequently leading to deficits in neurological function. Stroke …

Background Hypocholesterolemia is the most frequently encountered lipid abnormality in
sickle cell disease (SCD). We enrolled pediatric patients to determine the relationships …

Introduction. Clinical complications in sickle cell anemia (SCA) are heterogeneous and
involve several molecules. It has been suggested that SCA individuals present a …

Sickle cell disease (SCD) patients often exhibit a dyslipidemic sub-phenotype. Paraoxonase
1 (PON 1) is a serum glycoprotein associated with the high-density lipoproteins cholesterol …

Background Previous study has shown that dyslipidemia is common in patients with Sickle
cell disease (SCD) and is associated with more serious SCD complications. Methods This …

Background. Abnormal lipid homeostasis in sickle cell disease (SCD) is characterized by
defects in plasma and erythrocyte lipids and may increase the risk of cardiovascular …

Background. Lipid metabolism may be altered in red cell genetic disorders. The erythrocyte
and plasma lipids are defected which may increase the risk of cardiovascular disease. In the …

Background: Lipid and electrocardiographic (ECG) abnormalities have been reported in
adults with sickle cell anaemia (SCA) and may reflect underlying structural and/or functional …

This cross-sectional study investigated associations between SNPs in metabolizing lipid
genes, alpha-thalassemia and laboratory parameters in two forms of sickle cell disease …