Human papillomavirus infection and the multistage carcinogenesis of cervical cancer

M Schiffman, N Wentzensen - Cancer epidemiology, biomarkers & …, 2013 - AACR
This short review outlines our understanding of cervical cancer precursors, concentrating on
the central etiologic role of persistent human papillomavirus infection. The stages of cervical …

Smoking habit, immune suppression, oral contraceptive use, and hormone replacement therapy use and cervical carcinogenesis: a review of the literature

A Gadducci, C Barsotti, S Cosio… - Gynecological …, 2011 - Taylor & Francis
High-risk human papillomaviruses (HPVs) are involved in the etiopathogenesis of cervical
intraepithelial neoplasia (CIN) and cervical cancer. After taking HPV into account, smoking …

DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway

L Lau, EE Gray, RL Brunette, DB Stetson - Science, 2015 - science.org
Cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS) detects
intracellular DNA and signals through the adapter protein STING to initiate the antiviral …

Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma

HS Chahal, Y Lin, KJ Ransohoff, DA Hinds… - Nature …, 2016 - nature.com
Cutaneous squamous cell carcinoma represents the second most common cutaneous
malignancy, affecting 7–11% of Caucasians in the United States. The genetic determinants …

[HTML][HTML] HPV-related cancers after solid organ transplantation in the United States

MM Madeleine, JL Finch, CF Lynch… - American journal of …, 2013 - Elsevier
Transplant recipients have elevated cancer risk including risk of human papillomavirus
(HPV)-associated cancers of the cervix, anus, penis, vagina, vulva and oropharynx. We …

Defining the genetic susceptibility to cervical neoplasia—A genome-wide association study

PJ Leo, MM Madeleine, S Wang, SM Schwartz… - PLoS …, 2017 - journals.plos.org
A small percentage of women with cervical HPV infection progress to cervical neoplasia,
and the risk factors determining progression are incompletely understood. We sought to …

TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies

SJ Klug, M Ressing, J Koenig, MC Abba… - The lancet …, 2009 - thelancet.com
Background Cervical cancer is caused primarily by human papillomaviruses (HPV). The
polymorphism rs1042522 at codon 72 of the TP53 tumour-suppressor gene has been …

Niche adaptation and viral transmission of human papillomaviruses from archaic hominins to modern humans

Z Chen, R DeSalle, M Schiffman, R Herrero… - PLoS …, 2018 - journals.plos.org
Recent discoveries on the origins of modern humans from multiple archaic hominin
populations and the diversity of human papillomaviruses (HPVs) suggest a complex …

Association of HLA‐DRB1, interleukin‐6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population—a candidate gene approach

FA Castro, K Haimila, I Sareneva… - … journal of cancer, 2009 - Wiley Online Library
High‐risk human papillomavirus (hrHPV) infection is the major risk factor for cervical cancer
(CxCa). The role of genetic susceptibility in the disease has been suggested, but the existing …

Human Leukocyte Antigens and Systemic Lupus Erythematosus: A Protective Role for the HLA-DR6 Alleles DRB1*13:02 and *14:03

H Furukawa, A Kawasaki, S Oka, I Ito, K Shimada… - PloS one, 2014 - journals.plos.org
Many studies on associations between human leukocyte antigen (HLA) allele frequencies
and susceptibility to systemic lupus erythematosus (SLE) have been performed. However …