Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era

S Castañeda-Barba, EM Top, T Stalder - Nature Reviews Microbiology, 2024 - nature.com
Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …

Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae

YL Han, XH Wen, W Zhao, XS Cao, JX Wen… - Frontiers in …, 2022 - frontiersin.org
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella
pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can …

A randomized, double-blind, multicenter trial comparing efficacy and safety of imipenem/cilastatin/relebactam versus piperacillin/tazobactam in adults with hospital …

I Titov, RG Wunderink, A Roquilly… - Clinical Infectious …, 2021 - academic.oup.com
Background Imipenem combined with the β-lactamase inhibitor relebactam has broad
antibacterial activity, including against carbapenem-resistant gram-negative pathogens. We …

[HTML][HTML] A review of Spaulding's classification system for effective cleaning, disinfection and sterilization of reusable medical devices: Viewed through a modern-day …

NJ Rowan, T Kremer, G McDonnell - Science of the Total Environment, 2023 - Elsevier
Despite advances in medicine and innovations in many underpinning fields including
disease prevention and control, the Spaulding classification system, originally proposed in …

Association between antibiotic resistance and increasing ambient temperature in China: an ecological study with nationwide panel data

W Li, C Liu, HC Ho, L Shi, Y Zeng, X Yang… - The Lancet Regional …, 2023 - thelancet.com
Background Antibiotic resistance leads to longer hospital stays, higher medical costs, and
increased mortality. However, research into the relationship between climate change and …

[HTML][HTML] “Superbugs” with hypervirulence and carbapenem resistance in Klebsiella pneumoniae: the rise of such emerging nosocomial pathogens in China

D Pu, J Zhao, K Chang, X Zhuo, B Cao - Science Bulletin, 2023 - Elsevier
Although hypervirulent Klebsiella pneumoniae (hvKP) can produce community-acquired
infections that are fatal in young and adult hosts, such as pyogenic liver abscess …

Geographic patterns of carbapenem-resistant Pseudomonas aeruginosa in the Asia-Pacific Region: results from the Antimicrobial Testing Leadership and …

YL Lee, WC Ko, PR Hsueh - Antimicrobial agents and …, 2022 - Am Soc Microbiol
Pseudomonas aeruginosa is a common pathogen that is associated with multidrug-resistant
(MDR) and carbapenem-resistant (CR) phenotypes; therefore, we investigated its resistance …

[HTML][HTML] Carbapenemase-producing Gram-negative bacteria in aquatic environments: A review

Z Cherak, L Loucif, A Moussi, JM Rolain - Journal of Global Antimicrobial …, 2021 - Elsevier
Antibiotic resistance is one of the greatest public-health challenges worldwide, especially
with regard to Gram-negative bacteria (GNB). Carbapenems are the β-lactam antibiotics of …

Antibiotic-resistant ESKAPE pathogens and COVID-19: the pandemic beyond the pandemic

A Catalano, D Iacopetta, J Ceramella, M Pellegrino… - Viruses, 2023 - mdpi.com
Antibacterial resistance is a renewed public health plague in modern times, and the COVID-
19 pandemic has rekindled this problem. Changes in antibiotic prescribing behavior …

Antimicrobial activities and mode of flavonoid actions

A Thebti, A Meddeb, I Ben Salem, C Bakary, S Ayari… - Antibiotics, 2023 - mdpi.com
The emergence of antibiotics-resistant bacteria has been a serious concern for medical
professionals over the last decade. Therefore, developing new and effective antimicrobials …