Noble metals in medicine: Latest advances
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
New trends in platinum and palladium complexes as antineoplastic agents
The discovery of cisplatin (cis-Pt (NH 3) 2 Cl 2) as an antineoplastic agent has focussed
attention on the rational design of metal complexes that can be potentially used in cancer …
attention on the rational design of metal complexes that can be potentially used in cancer …
Comprehensive review on tumour active palladium compounds and structure–activity relationships
MN Alam, F Huq - Coordination Chemistry Reviews, 2016 - Elsevier
This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …
New compounds based on a benzimidazole nucleus: synthesis, characterization and cytotoxic activity against breast and colon cancer cell lines
Benzimidazolium salts and their Pyridine Enhanced Precatalyst Preparation Stabilization
and I nitiation (PEPPSI) palladium N-heterocyclic carbene (Pd-NHC) based complexes have …
and I nitiation (PEPPSI) palladium N-heterocyclic carbene (Pd-NHC) based complexes have …
Developing a novel indium (III) agent based on liposomes to overcome cisplatin-induced resistance in breast cancer by multitargeting the tumor microenvironment …
M Jiang, Y Chu, T Yang, W Li, Z Zhang… - Journal of Medicinal …, 2021 - ACS Publications
To overcome the resistance of cancer cells to platinum-based drugs and effectively suppress
tumor growth, we developed a novel indium (In) agent based on liposomes (Lips). Thus, we …
tumor growth, we developed a novel indium (In) agent based on liposomes (Lips). Thus, we …
Synthesis, characterization and anticancer activity of new 2-acetyl-5-methyl thiophene and cinnamaldehyde thiosemicarbazones and their palladium (II) complexes
New thiosemicarbazone (TSC) ligands, AMT-Cdouble bondN-TSCH (L1), AMT-Cdouble
bondN-TSC (CH 3)(L2), CIN-Cdouble bondN-TSCH (L3) and CIN-Cdouble bondN-TSC (CH …
bondN-TSC (CH 3)(L2), CIN-Cdouble bondN-TSCH (L3) and CIN-Cdouble bondN-TSC (CH …
Novel R-(+)-limonene-based thiosemicarbazones and their antitumor activity against human tumor cell lines
F Vandresen, H Falzirolli, SAA Batista… - European journal of …, 2014 - Elsevier
In an attempt to develop potent and selective antitumor agents, a series of novel
thiosemicarbazones derived from a natural monoterpene R-(+)-limonene was synthesized …
thiosemicarbazones derived from a natural monoterpene R-(+)-limonene was synthesized …
Removal of Transition-Metal Ions by Metal-Complexing Polythiosemicarbazone Membranes
Membrane technology is one of the many strategies to remove transition-metal ions from
aqueous streams because of its relatively lower costs and ease of operation. Typically …
aqueous streams because of its relatively lower costs and ease of operation. Typically …
Palladium and platinum complexes of folic acid as new drug delivery systems for treatment of breast cancer cells
Cisplatin is administrated as an agent in treatment of various cancers by intercalation
between DNA strands and inhibition of DNA replication. Among the various factors, two …
between DNA strands and inhibition of DNA replication. Among the various factors, two …
Mononuclear Pd (ii) and Pt (ii) complexes with an α-N-heterocyclic thiosemicarbazone: cytotoxicity, solution behaviour and interaction versus proven models from …
AI Matesanz, E Jimenez-Faraco, MC Ruiz… - Inorganic Chemistry …, 2018 - pubs.rsc.org
Two Pd (II) and Pt (II) complexes with two pyrrol-2-carbaldehyde Np-
chlorophenylthiosemicarbazone ligands are designed and characterized showing …
chlorophenylthiosemicarbazone ligands are designed and characterized showing …