Effects of maternal obesity on placental function and fetal development

KR Howell, TL Powell - Reproduction (Cambridge, England), 2016 - pmc.ncbi.nlm.nih.gov
Obesity has reached epidemic proportions and pregnancies in obese mothers have
increased risk for complications including gestational diabetes, hypertensive disorders …

Maternal serum cytokine concentrations in healthy pregnancy and preeclampsia

T Spence, PJ Allsopp, AJ Yeates… - Journal of …, 2021 - Wiley Online Library
The maternal immune response is essential for successful pregnancy, promoting immune
tolerance to the fetus while maintaining innate and adaptive immunity. Uncontrolled …

Association of pro‐and anti‐inflammatory cytokines in preeclampsia

R Aggarwal, AK Jain, P Mittal, M Kohli… - Journal of clinical …, 2019 - Wiley Online Library
Introduction The pro‐and anti‐inflammatory cytokines play crucial role in the development
and functions of placenta. Any changes in these cytokines may be associated with many …

Repeated measures of inflammation and oxidative stress biomarkers in preeclamptic and normotensive pregnancies

KK Ferguson, JD Meeker, TF McElrath… - American journal of …, 2017 - Elsevier
Background Preeclampsia is a prevalent and enigmatic disease, in part characterized by
poor remodeling of the spiral arteries. However, preeclampsia does not always clinically …

Inflammation, depression and cardiovascular disease in women: the role of the immune system across critical reproductive events

GF Mattina, RJ Van Lieshout… - Therapeutic advances in …, 2019 - journals.sagepub.com
Women are at increased risk for developing depression and cardiovascular disease (CVD)
across the lifespan and their comorbidity is associated with adverse outcomes that …

Inflammatory markers and preeclampsia: a systematic review

KD Black, JA Horowitz - Nursing research, 2018 - journals.lww.com
Background Preeclampsia (PE), a serious and variable pregnancy complication affecting
5%–10% of the obstetric population, has an undetermined etiology, yet inflammation is …

Preeclampsia among African American pregnant women: an update on prevalence, complications, etiology, and biomarkers

M Zhang, P Wan, K Ng, K Singh… - Obstetrical & …, 2020 - journals.lww.com
Preeclampsia Among African American Pregnant Women: An Updat... : Obstetrical &
Gynecological Survey Preeclampsia Among African American Pregnant Women: An Update …

A systematic review of the safety of blocking the IL-1 system in human pregnancy

ME Brien, V Gaudreault, K Hughes, DJL Hayes… - Journal of Clinical …, 2021 - mdpi.com
Blockade of the interleukin-1 (IL-1) pathway has been used therapeutically in several
inflammatory diseases including arthritis and cryopyrin-associated periodic syndrome …

Preeclamptic women have decreased circulating IL-10 (Interleukin-10) values at the time of preeclampsia diagnosis: systematic review and meta-analysis

MC Nath, H Cubro, DJ McCormick, NM Milic… - …, 2020 - Am Heart Assoc
A key immunomodulatory cytokine, IL-10 (interleukin-10), has been shown to be
dysregulated in preeclampsia, a pregnancy-specific hypertensive disorder, further …

The impact of female fetal sex on preeclampsia and the maternal immune milieu

BD Taylor, RB Ness, MA Klebanoff, G Tang… - Pregnancy …, 2018 - Elsevier
Objective Small studies suggest that fetal sex alters maternal inflammation. We examined
the association between fetal sex, preeclampsia and circulating maternal immune markers …