Eicosanoids and cancer
RN Gomes, S Felipe da Costa, A Colquhoun - Clinics, 2018 - SciELO Brasil
Eicosanoids are 20-carbon bioactive lipids derived from the metabolism of polyunsaturated
fatty acids, which can modulate various biological processes including cell proliferation …
fatty acids, which can modulate various biological processes including cell proliferation …
Mechanisms and clinical significance of tumor lymphatic invasion
N Fujimoto, LC Dieterich - Cells, 2021 - mdpi.com
Tumor-associated lymphatic vessels play an important role in tumor progression, mediating
lymphatic dissemination of malignant cells to tumor-draining lymph nodes and regulating …
lymphatic dissemination of malignant cells to tumor-draining lymph nodes and regulating …
Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling
S Stadler, CH Nguyen, H Schachner… - Cellular and Molecular …, 2017 - Springer
Retraction of mesenchymal stromal cells supports the invasion of colorectal cancer cells
(CRC) into the adjacent compartment. CRC-secreted 12 (S)-HETE enhances the retraction …
(CRC) into the adjacent compartment. CRC-secreted 12 (S)-HETE enhances the retraction …
Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro
J Hong, A Fristiohady, CH Nguyen… - Frontiers in …, 2018 - frontiersin.org
Flavonoids, present in fruits, vegetables and traditional medicinal plants, show anticancer
effects in experimental systems and are reportedly non-toxic. This is a favorable property for …
effects in experimental systems and are reportedly non-toxic. This is a favorable property for …
An integrated strategy for the identification and screening of anti-allergy components from natural products based on calcium fluctuations and cell extraction coupled …
G Hu, X Li, J Zhang, L Zhang, J Qi, B Yu - Analytical and Bioanalytical …, 2021 - Springer
Allergic diseases are a significant public health problem worldwide. Traditional Chinese
medicines (TCMs) with reported anti-allergy effects may be important sources for the …
medicines (TCMs) with reported anti-allergy effects may be important sources for the …
Role of oxylipins generated from dietary PUFAs in the modulation of endothelial cell function
Y Du, CG Taylor, HM Aukema, P Zahradka - … , Leukotrienes and Essential …, 2020 - Elsevier
Oxylipins, which are circulating bioactive lipids generated from polyunsaturated fatty acids
(PUFAs) by cyclooxygenase, lipooxygenase and cytochrome P450 enzymes, have diverse …
(PUFAs) by cyclooxygenase, lipooxygenase and cytochrome P450 enzymes, have diverse …
Unraveling the role of 12-and 20-HETE in cardiac pathophysiology: G-protein–coupled receptors, pharmacological inhibitors, and transgenic approaches
JV Pascale, PA Lucchesi, V Garcia - Journal of cardiovascular …, 2021 - journals.lww.com
Arachidonic acid–derived lipid mediators play crucial roles in the development and
progression of cardiovascular diseases. Eicosanoid metabolites generated by …
progression of cardiovascular diseases. Eicosanoid metabolites generated by …
[HTML][HTML] Circular RNA-mediated miRNA sponge & RNA binding protein in biological modulation of breast cancer
J Zhu, Q Li, Z Wu, W Xu, R Jiang - Non-coding RNA Research, 2024 - Elsevier
Circular RNAs (circRNAs) and small non-coding RNAs of the head-to-junction circle in the
construct play critical roles in gene regulation and are significantly associated with breast …
construct play critical roles in gene regulation and are significantly associated with breast …
Investigation of the content differences of arachidonic acid metabolites in a mouse model of breast cancer by using LC–MS/MS
A Chen, Y Zhang, D Sun, Y Xu, Y Guo… - Journal of Pharmaceutical …, 2021 - Elsevier
Arachidonic acid (AA) is closely associated with breast cancer. In addition to the two
metabolic pathways regulated by cyclooxygenase and lipoxygenase, AA has a third …
metabolic pathways regulated by cyclooxygenase and lipoxygenase, AA has a third …
Female mice carrying a defective Alox15 gene are protected from experimental colitis via sustained maintenance of the intestinal epithelial barrier function
S Kroschwald, CY Chiu, D Heydeck, N Rohwer… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Lipoxygenases (ALOXs) are involved in the regulation of cellular redox homeostasis. They
also have been implicated in the biosynthesis of pro-and anti-inflammatory lipid mediators …
also have been implicated in the biosynthesis of pro-and anti-inflammatory lipid mediators …