Challenges in liver cancer and possible treatment approaches

D Anwanwan, SK Singh, S Singh, V Saikam… - Biochimica et Biophysica …, 2020 - Elsevier
Globally, liver cancer is the most frequent fatal malignancy; in the United States, it ranks fifth.
Patients are often diagnosed with liver cancer in advanced stages, contributing to its poor …

Evaluation of biological activity of natural compounds: current trends and methods

C Barba-Ostria, SE Carrera-Pacheco… - Molecules, 2022 - mdpi.com
Natural compounds have diverse structures and are present in different forms of life.
Metabolites such as tannins, anthocyanins, and alkaloids, among others, serve as a defense …

Chitosan-encapsulated nickel oxide, tin dioxide, and farnesol nanoparticles: antimicrobial and anticancer properties in breast cancer cells

S Mickymaray, MS Al Aboody, MM Eraqi… - International Journal of …, 2023 - Elsevier
Breast cancer is the most frequent cancer in women; however, it is curable in most cases (up
to 80%) when detected and treated at an early non-metastatic stage. Nanotechnology has …

[HTML][HTML] Cepharanthine inhibits hepatocellular carcinoma cell growth and proliferation by regulating amino acid metabolism and suppresses tumorigenesis in vivo

F Feng, L Pan, J Wu, L Li, H Xu, L Yang… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Cepharanthine (CEP), a natural compound extracted from Stephania cepharantha Hayata,
has been found to have the potential to treat a variety of tumors in recent years. This study …

Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma

MF Mohamed, NS Ibrahim, AA Saddiq… - Scientific Reports, 2023 - nature.com
A novel series of α-cyano indolylchalcones was prepared, and their chemical structures
were confirmed based on the different spectral data. Among them, compound 7f was …

Phytochemical Analysis and In Vitro Effects of Allium fistulosum L. and Allium sativum L. Extracts on Human Normal and Tumor Cell Lines: A Comparative Study

AB Țigu, CS Moldovan, VA Toma, AD Farcaș, AC Moț… - Molecules, 2021 - mdpi.com
Allium sativum L.(garlic bulbs) and Allium fistulosum L.(Welsh onion leaves) showed
quantitative differences of identified compounds: allicin and alliin (380 µg/mL and 1410 …

Prodigiosin/PU-H71 as a novel potential combined therapy for triple negative breast cancer (TNBC): preclinical insights

MM Anwar, M Shalaby, AM Embaby, H Saeed… - Scientific Reports, 2020 - nature.com
Prodigiosin, a secondary metabolite red pigment produced by Serratia marcescens, has an
interesting apoptotic efficacy against cancer cell lines with low or no toxicity on normal cells …

Nickel-doped vanadium pentoxide (Ni@ V2O5) nanocomposite induces apoptosis targeting PI3K/AKT/mTOR signaling pathway in skin cancer: An in vitro and in vivo …

S Nivetha, T Srivalli, PM Sathya, H Mohan… - Colloids and Surfaces B …, 2024 - Elsevier
In the present study, the vanadium pentoxide (V 2 O 5) nickel-doped vanadium pentoxide
(Ni@ V 2 O 5) was prepared and determined for in vitro anticancer activity. The structural …

Artemisia argyi extract induces apoptosis in human gemcitabine-resistant lung cancer cells via the PI3K/MAPK signaling pathway

SH Su, N Sundhar, WW Kuo, SC Lai, CH Kuo… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance: Artemisia argyi H. Lév. & Vaniot (Asteraceae), also called
“Chinese mugwort”, is frequently used as a herbal medicine in China, Japan, Korea, and …

Moringa oleifera methanolic leaves extract induces apoptosis and G0/G1 cell cycle arrest via downregulation of Hedgehog Signaling Pathway in human prostate PC …

F Khan, P Pandey, V Ahmad… - Journal of food …, 2020 - Wiley Online Library
The inadequacy of effective treatment approaches for prostate cancer enlightens the crucial
necessity for the search and emergence of novel and multitasking anticancer substances …