Iron Oxide Nanoparticles as T1 Contrast Agents for Magnetic Resonance Imaging: Fundamentals, Challenges, Applications, and Prospectives

M Jeon, MV Halbert, ZR Stephen… - Advanced Materials, 2021 - Wiley Online Library
Gadolinium‐based chelates are a mainstay of contrast agents for magnetic resonance
imaging (MRI) in the clinic. However, their toxicity elicits severe side effects and the Food …

[HTML][HTML] Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics

S Zhao, X Yu, Y Qian, W Chen, J Shen - Theranostics, 2020 - ncbi.nlm.nih.gov
Multifunctional magnetic nanoparticles and derivative nanocomposites have aroused great
concern for multimode imaging and cancer synergistic therapies in recent years. Among the …

Magnetic nanoparticles in biology and medicine: past, present, and future trends

DD Stueber, J Villanova, I Aponte, Z Xiao, VL Colvin - Pharmaceutics, 2021 - mdpi.com
The use of magnetism in medicine has changed dramatically since its first application by the
ancient Greeks in 624 BC. Now, by leveraging magnetic nanoparticles, investigators have …

Ultrasmall superparamagnetic iron oxide nanoparticles: A next generation contrast agent for magnetic resonance imaging

C Chen, J Ge, Y Gao, L Chen, J Cui… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
As a research hotspot, the development of magnetic resonance imaging (MRI) contrast
agents has attracted great attention over the past decades for improving the accuracy of …

[HTML][HTML] Recent advances in engineering iron oxide nanoparticles for effective magnetic resonance imaging

Z Zhao, M Li, J Zeng, L Huo, K Liu, R Wei, K Ni, J Gao - Bioactive Materials, 2022 - Elsevier
Iron oxide nanoparticle (IONP) with unique magnetic property and high biocompatibility
have been widely used as magnetic resonance imaging (MRI) contrast agent (CA) for long …

[HTML][HTML] Natural polyphenols in drug delivery systems: Current status and future challenges

H Wang, C Wang, Y Zou, J Hu, Y Li, Y Cheng - Giant, 2020 - Elsevier
Natural polyphenols have attracted great interests in medicine, food and cosmetics due to
their versatile functions such as antioxidant, anticancer and antibacterial. The polyphenolic …

Magnetic iron oxide nanoparticles as T 1 contrast agents for magnetic resonance imaging

Y Bao, JA Sherwood, Z Sun - Journal of Materials Chemistry C, 2018 - pubs.rsc.org
Ultrasmall iron oxide nanoparticles have recently attracted much attention as T1 (positive)
contrast agents for magnetic resonance imaging to serve as safer alternatives to gadolinium …

Exceedingly Small Magnetic Iron Oxide Nanoparticles for T1‐Weighted Magnetic Resonance Imaging and Imaging‐Guided Therapy of Tumors

J Yang, J Feng, S Yang, Y Xu, Z Shen - Small, 2023 - Wiley Online Library
Magnetic iron oxide nanoparticles (MIONs) based T2‐weighted magnetic resonance
imaging (MRI) contrast agents (CAs) are liver‐specific with good biocompatibility, but have …

Imaging constructs: the rise of iron oxide nanoparticles

BEB Crețu, G Dodi, A Shavandi, I Gardikiotis… - Molecules, 2021 - mdpi.com
Over the last decade, an important challenge in nanomedicine imaging has been the work to
design multifunctional agents that can be detected by single and/or multimodal techniques …

The Transition from Metal-Based to Metal-Free Contrast Agents for T1 Magnetic Resonance Imaging Enhancement

OU Akakuru, MZ Iqbal, M Saeed, C Liu… - Bioconjugate …, 2019 - ACS Publications
Magnetic resonance imaging (MRI) has received significant attention as the noninvasive
diagnostic technique for complex diseases. Image-guided therapeutic strategy for diseases …