Abstract 3D printed bone scaffolds have the potential to replace autografts and allografts
because of advantages such as unlimited supply and the ability to tailor the scaffolds' …

The treatment of bone defects is an important problem in clinical practice. The rapid
development of bone tissue engineering (BTE) may provide a new method for bone defect …

Critical-sized bone defect repair in patients with diabetes mellitus remains a challenge in
clinical treatment because of dysfunction of macrophage polarization and the inflammatory …

While ceramic additive manufacturing (AM) technologies have shown great promise to
create functional scaffolds with tailored biomechanical properties, the true potential of these …

Recent years have witnessed surging demand for bone repair/regeneration implants due to
the increasing number of bone defects caused by trauma, cancer, infection, and arthritis …

Over the past few decades, the field of biomaterials concerning bone tissue engineering has
gained a significant amount of interest. This has led to new biomaterials to be used as bone …

Osteoinductivity of a biomaterial scaffold can notably enhance the bone healing
performance. In this study, we developed a biomimetic and hierarchically porous …

Although additive manufacturing has offered substantially new opportunities and flexibility
for fabricating 3D complex lattice structures, effective design of such sophisticated structures …

Critical-size bone defects, which require large-volume tissue reconstruction, remain a
clinical challenge. Bone engineering has the potential to provide new treatment concepts …

In clinical terms, bone grafting currently involves the application of autogenous, allogeneic,
or xenogeneic bone grafts, as well as natural or artificially synthesized materials, such as …