Coagulation factor XIII (FXIII) acts as a fine fulcrum in blood plasma that maintains the
balance between bleeding and thrombosis by covalently crosslinking the pre-formed fibrin …

Factor XIII deficiency (FXIIID) is an extremely rare autosomal recessive disorder that has the
highest incidence in Iran. The FXIIID is primarily due to mutations in the FXIII-A gene, most of …

Congenital bleeding disorders (CBDs) are a heterogeneous group of disorders with variable
clinical presentations ranging from asymptomatic conditions, mostly in inherited platelet …

Diagnosis of factor XIII (FXIII) deficiency (FXIIID) as a rare bleeding disorder is a challenge
worldwide. Thus, in the present study, we used different methods including two molecular …

Factor XIII (FXIII) is a transglutaminase that in addition to its well-known role in coagulation
cascade has a crucial role in angiogenesis, wound healing, bone metabolism, and …

Background: Factor XIII deficiency is one of the most severe congenital bleeding disorders
with high rate of lifethreatening bleeding including central nervous system bleeding …

Congenital bleeding disorders (CBD) are heterogeneous group of hemorrhagic disorders
with highly variable incidence, clinical presentations, and laboratory findings [1, 2]. Although …