[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

Antimicrobial peptides–Advances in development of therapeutic applications

HX Luong, TT Thanh, TH Tran - Life sciences, 2020 - Elsevier
The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …

Paracrine mechanisms of mesenchymal stem cells in tissue repair

M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …

Current evidence on the bioavailability of food bioactive peptides

L Amigo, B Hernández-Ledesma - Molecules, 2020 - mdpi.com
Food protein-derived bioactive peptides are recognized as valuable ingredients of functional
foods and/or nutraceuticals to promote health and reduce the risk of chronic diseases …

Approaches for enhancing oral bioavailability of peptides and proteins

J Renukuntla, AD Vadlapudi, A Patel… - International journal of …, 2013 - Elsevier
Oral delivery of peptide and protein drugs faces immense challenge partially due to the
gastrointestinal (GI) environment. In spite of considerable efforts by industrial and academic …

Lipid-based nanovesicles for nanomedicine

N Grimaldi, F Andrade, N Segovia… - Chemical society …, 2016 - pubs.rsc.org
Molecular self-assembly has enabled the fabrication of biologically inspired, advanced
nanostructures as lipid-based nanovesicles (L-NVs). The oldest L-NVs, liposomes, have …

Paracrine mechanisms in adult stem cell signaling and therapy

M Gnecchi, Z Zhang, A Ni, VJ Dzau - Circulation research, 2008 - Am Heart Assoc
Animal and preliminary human studies of adult cell therapy following acute myocardial
infarction have shown an overall improvement of cardiac function. Myocardial and vascular …

A review of advanced oral drug delivery technologies facilitating the protection and absorption of protein and peptide molecules

BF Choonara, YE Choonara, P Kumar… - Biotechnology …, 2014 - Elsevier
The oral delivery of proteins and peptides is a dynamic research field despite the numerous
challenges limiting their effective delivery. Successful oral delivery of proteins and peptides …

Paracrine mechanisms of stem cell reparative and regenerative actions in the heart

M Mirotsou, TM Jayawardena, J Schmeckpeper… - Journal of molecular and …, 2011 - Elsevier
Stem cells play an important role in restoring cardiac function in the damaged heart. In order
to mediate repair, stem cells need to replace injured tissue by differentiating into specialized …

Conus venom peptide pharmacology

RJ Lewis, S Dutertre, I Vetter, MDJ Christie - Pharmacological reviews, 2012 - ASPET
Conopeptides are a diverse group of recently evolved venom peptides used for prey capture
and/or defense. Each species of cone snails produces in excess of 1000 conopeptides, with …