Pharmacological therapy for glaucoma: a review
PFJ Hoyng, LM van Beek - Drugs, 2000 - Springer
For some time the medical treatment of glaucoma has consisted of topical β-blockers,
adrenergic agents, miotics and oral carbonic anhydrase inhibitors (CAIs). However, the …
adrenergic agents, miotics and oral carbonic anhydrase inhibitors (CAIs). However, the …
Prostaglandins in the eye: Function, expression, and roles in glaucoma
LP Doucette, MA Walter - Ophthalmic genetics, 2017 - Taylor & Francis
Prostaglandins are small pro-inflammatory molecules derived from arachidonic acid that
play roles in a multitude of biological processes including, but not limited to, inflammation …
play roles in a multitude of biological processes including, but not limited to, inflammation …
A comparison of latanoprost, bimatoprost, and travoprost in patients with elevated intraocular pressure:: A 12-week, randomized, masked-evaluator multicenter study
RK Parrish, P Palmberg, WP Sheu… - American journal of …, 2003 - Elsevier
PURPOSE: To Internet Advance publication at ajo. com Feb 13, 2003. compare the
intraocular pressure (IOP)-lowering effect and safety of latanoprost, bimatoprost, and …
intraocular pressure (IOP)-lowering effect and safety of latanoprost, bimatoprost, and …
Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility
M Honjo, H Tanihara, M Inatani, N Kido… - … & visual science, 2001 - iovs.arvojournals.org
purpose. To elucidate the roles of Rho-associated protein kinase (ROCK) in regulating
intraocular pressure (IOP) and outflow facility in the rabbit eye. methods. A specific ROCK …
intraocular pressure (IOP) and outflow facility in the rabbit eye. methods. A specific ROCK …
Effects of topical administration of y-39983, a selective rho-associated protein kinase inhibitor, on ocular tissues in rabbits and monkeys
H Tokushige, M Inatani, S Nemoto… - … & visual science, 2007 - iovs.arvojournals.org
purpose. To elucidate the intraocular pressure (IOP)–lowering effects and associated
characteristics of Y-39983, a selective Rho-associated coiled coil-forming protein kinase …
characteristics of Y-39983, a selective Rho-associated coiled coil-forming protein kinase …
Ocular hypotensive FP prostaglandin (PG) analogs: PG receptor subtype binding affinities and selectivities, and agonist potencies at FP and other PG receptors in …
NA Sharif, CR Kelly, JY Crider… - Journal of Ocular …, 2003 - liebertpub.com
Natural prostaglandins (PGs) such as PGD2, PGE2, PGF22 α, and PGI2 exhibited the
highest affinity for their respective cognate receptors, but were the least selective agents …
highest affinity for their respective cognate receptors, but were the least selective agents …
Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug
Y Takagi, T Nakajima, A Shimazaki… - Experimental eye …, 2004 - Elsevier
To evaluate the pharmacological characteristics of AFP-168 (tafluprost), a new
prostaglandin (PG) F2α derivative, we examined its receptor-binding affinities, intraocular …
prostaglandin (PG) F2α derivative, we examined its receptor-binding affinities, intraocular …
The effects of antiglaucoma and systemic medications on ocular blood flow
Based on the body of evidence implicating ocular blood flow disturbances in the
pathogenesis of glaucoma, there is great interest in the investigation of the effects of …
pathogenesis of glaucoma, there is great interest in the investigation of the effects of …
Effects of protein kinase inhibitor, HA1077, on intraocular pressure and outflow facility in rabbit eyes
M Honjo, M Inatani, N Kido, T Sawamura… - Archives of …, 2001 - jamanetwork.com
Objective To elucidate the roles of protein kinase in regulating the intraocular pressure (IOP)
and outflow facility in rabbit eyes. Materials and Methods A protein kinase inhibitor, 1-(5 …
and outflow facility in rabbit eyes. Materials and Methods A protein kinase inhibitor, 1-(5 …
[HTML][HTML] Human trabecular meshwork cell responses induced by bimatoprost, travoprost, unoprostone, and other FP prostaglandin receptor agonist analogues
NA Sharif, CR Kelly, JY Crider - Investigative ophthalmology & …, 2003 - jov.arvojournals.org
purpose. To determine the functional agonist potencies of the intraocular pressure (IOP)-
lowering prostaglandin F (FP)-class prostaglandin (PG) analogues (eg, travoprost …
lowering prostaglandin F (FP)-class prostaglandin (PG) analogues (eg, travoprost …