[HTML][HTML] Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis

W Chen, M Schilperoort, Y Cao, J Shi, I Tabas… - Nature Reviews …, 2022 - nature.com
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …

[HTML][HTML] Protein-based nanoparticles as drug delivery systems

S Hong, DW Choi, HN Kim, CG Park, W Lee, HH Park - Pharmaceutics, 2020 - mdpi.com
Pharmaceutics | Free Full-Text | Protein-Based Nanoparticles as Drug Delivery Systems Next
Article in Journal Exploiting Lipid and Polymer Nanocarriers to Improve the Anticancer …

Apolipoproteins in vascular biology and atherosclerotic disease

A Mehta, MD Shapiro - Nature Reviews Cardiology, 2022 - nature.com
Apolipoproteins are important structural components of plasma lipoproteins that influence
vascular biology and atherosclerotic disease pathophysiology by regulating lipoprotein …

HDL and reverse cholesterol transport: Basic mechanisms and their roles in vascular health and disease

M Ouimet, TJ Barrett, EA Fisher - Circulation research, 2019 - Am Heart Assoc
Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …

High-density lipoprotein revisited: biological functions and clinical relevance

A von Eckardstein, BG Nordestgaard… - European heart …, 2023 - academic.oup.com
Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …

[HTML][HTML] Combating physical inactivity during the COVID-19 pandemic

AJ Pinto, DW Dunstan, N Owen, E Bonfá… - Nature Reviews …, 2020 - nature.com
Physical inactivity is common during periods of self-isolation, but for patients with rheumatic
diseases, there are crucial benefits to be gained from maintaining an active lifestyle …

[HTML][HTML] Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017

AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Effect of evolocumab on progression of coronary disease in statin-treated patients: the GLAGOV randomized clinical trial

SJ Nicholls, R Puri, T Anderson, CM Ballantyne, L Cho… - Jama, 2016 - jamanetwork.com
Importance Reducing levels of low-density lipoprotein cholesterol (LDL-C) with intensive
statin therapy reduces progression of coronary atherosclerosis in proportion to achieved …

Atherosclerotic cardiovascular disease prevention in rheumatoid arthritis

AG Semb, E Ikdahl, G Wibetoe, C Crowson… - Nature Reviews …, 2020 - nature.com
Patients with rheumatoid arthritis (RA) are at high risk of developing cardiovascular disease
(CVD). Inflammation has a pivotal role in the pathogenesis of CVD. RA is an inflammatory …

Cholesterol, inflammation and innate immunity

AR Tall, L Yvan-Charvet - Nature Reviews Immunology, 2015 - nature.com
Hypercholesterolaemia leads to cholesterol accumulation in macrophages and other
immune cells, which promotes inflammatory responses, including augmentation of Toll-like …