[HTML][HTML] Endocytosis: the nanoparticle and submicron nanocompounds gateway into the cell

D Manzanares, V Ceña - Pharmaceutics, 2020 - mdpi.com
Nanoparticles (NPs) and submicron particles are increasingly used as carriers for delivering
therapeutic compounds to cells. Their entry into the cell represents the initial step in this …

The biophysicochemical interactions at the interfaces between nanoparticles and aquatic organisms: adsorption and internalization

S Ma, D Lin - Environmental Science: Processes & Impacts, 2013 - pubs.rsc.org
Nano–bio interfacial interactions that can likely regulate the potential toxicity of
nanoparticles (NPs) toward aquatic organisms are receiving increasing research interest …

Engineering of cascade-responsive nanoplatform to inhibit lactate efflux for enhanced tumor chemo-immunotherapy

K Li, C Lin, Y He, L Lu, K Xu, B Tao, Z Xia, R Zeng… - ACS …, 2020 - ACS Publications
As an increased product of high-rate aerobic glycolysis in tumors, lactate could regulate the
immunosuppressive tumor microenvironment (TME). A PEG-CDM surface modified, GSH …

Distinction between active and passive targeting of nanoparticles dictate their overall therapeutic efficacy

TD Clemons, R Singh, A Sorolla, N Chaudhari… - Langmuir, 2018 - ACS Publications
The role of nanoparticles in cancer medicine is vast with debate still surrounding the
distinction between therapeutic efficacy of actively targeted nanoparticles versus passively …

Polycation-mediated transfection: Mechanisms of internalization and intracellular trafficking

BD Monnery - Biomacromolecules, 2021 - ACS Publications
Polyplex-mediated gene transfection is now in its' fourth decade of serious research, but the
promise of polyplex-mediated gene therapy has yet to fully materialize. Only approximately …

Covalent grafting interface engineering to prepare highly efficient and stable polypropylene/mesoporous SiO2 separator for Li-ion batteries

X Qi, Z Zhang, C Tu, C Zhu, J Wei, Z Yang - Applied Surface Science, 2021 - Elsevier
Due to the deficiency of low melting point and poor wettability of commercial polyolefin
separators, the design and development of ceramic coating separators have been received …

pH-responsive and charge shielded cationic micelle of poly (L-histidine)-block-short branched PEI for acidic cancer treatment

J Hu, S Miura, K Na, YH Bae - Journal of Controlled Release, 2013 - Elsevier
To address cancer cell heterogeneity while endowing tumor specificity, the approach of
charge shielding/deshielding was tested in vitro and in vivo with a paclitaxel loaded cationic …

Intrinsic Mitochondrial Reactive Oxygen Species (ROS) Activate the In Situ Synthesis of Trimethine Cyanines in Cancer Cells

H Heng, G Song, X Cai, J Sun, K Du… - Angewandte …, 2022 - Wiley Online Library
Environment‐responsive in situ synthesis of molecular fluorescent dyes is challenging.
Herein, we develop a photoextension strategy to make trimethine cyanines with decent …

Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1

J Han, BJ Zern, VV Shuvaev, PF Davies, S Muro… - ACS …, 2012 - ACS Publications
Intracellular delivery of nanocarriers (NC) is controlled by their design and target cell
phenotype, microenvironment, and functional status. Endothelial cells (EC) lining the …

Synthesis of an ethyleneimine/tetrahedral DNA nanostructure complex and its potential application as a multi-functional delivery vehicle

T Tian, T Zhang, T Zhou, S Lin, S Shi, Y Lin - Nanoscale, 2017 - pubs.rsc.org
Nowadays, DNA nanostructures are extensively researched for their biocompatibility,
editable functionality, and structural stability. Tetrahedral DNA nanostructures (TDNs) …