Inflammation is a vital defense mechanism, creating hostile conditions for pathogens,
preventing the spread of tissue infection and repairing damaged tissues in humans and …

Since their use during the First World War, Blister agents have posed a major threat to the
individuals and have caused around two million casualties. Major incidents occurred not …

Silibinin, a natural polyphenolic flavonoid, possesses anti-oxidant, anti-inflammation and
anti-cancer properties. The present study was designed to investigate the effects of silibinin …

Our recent studies in SKH-1 hairless mice have demonstrated that topical exposure to
nitrogen mustard (NM), an analog of sulfur mustard (SM), triggers the inflammatory …

Sulfur mustard (SM) and nitrogen mustard (NM) are vesicant agents that cause skin injury
and blistering through complicated cellular events, involving DNA damage, free radical …

Skin cancer incidences are rising worldwide, and one of the major causative factors is
excessive exposure to solar ultraviolet radiation (UVR). Annually,∼ 5 million skin cancer …

Sulfur mustard (SM) is a potent alkylating agent that targets several organs, especially lung
tissue. Although pathological effects of SM have been widely considered, molecular and …

Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation
and inflammation. Silibinin, a polyphenolic flavonoid derived from fruits and seeds of …

Sulfur mustard (SM) is a chemical warfare, which has been used for one hundred years.
However, its exact pathomechanisms are still incompletely understood and there is no …

Sulfur mustard (SM) is a chemical warfare agent that was applied in a series of military
conflicts and still poses a severe threat to civilians and military personnel. Although the …