The global burden of chronic urticaria for the patient and society

M Gonçalo, A Gimenéz‐Arnau… - British Journal of …, 2021 - academic.oup.com
Chronic urticaria (CU) affects about 1% of the world population of all ages, mostly young and
middle‐aged women. It usually lasts for several years (> 1 year in 25–75% of patients) and …

The pathogenesis of chronic spontaneous urticaria: the role of infiltrating cells

AM Giménez-Arnau, L de Montjoye, R Asero… - The Journal of Allergy …, 2021 - Elsevier
Chronic spontaneous urticaria is characterized by a perivascular non-necrotizing cellular
infiltrate around small venules of the skin. It consists primarily of CD4 (+) lymphocytes, a …

The role of eosinophils in chronic spontaneous urticaria

S Altrichter, S Frischbutter, JS Fok, P Kolkhir… - Journal of Allergy and …, 2020 - Elsevier
Chronic spontaneous urticaria (CSU) is considered to be primarily a mast cell–driven
disease. However, recent evidence suggests that eosinophils may also have an axial role in …

The diagnostic workup in chronic spontaneous urticaria—what to test and why

M Metz, S Altrichter, T Buttgereit, JW Fluhr… - The Journal of Allergy …, 2021 - Elsevier
Background In chronic spontaneous urticaria (CSU), the guidelines recommend very limited
diagnostic procedures during the routine workup, although additional investigations might …

Advanced biomarkers: therapeutic and diagnostic targets in urticaria

Y Zhang, H Zhang, S Du, S Yan, J Zeng - International archives of …, 2021 - karger.com
Urticaria is a type of skin disease characterized by rapid onset of hives (superficial dermis
edema, erythema, pruritus, or burning sensation). According to whether the natural course …

Biomarkers of chronic spontaneous urticaria and their clinical implications

R Asero, M Cugno - Expert review of clinical immunology, 2021 - Taylor & Francis
Introduction: Chronic spontaneous urticaria (CSU) is a frequent disorder in which activation
of effector cells and histamine release can be induced via several distinct pathogenetic …

Biomarkers in chronic spontaneous urticaria: current targets and clinical implications

I Puxeddu, F Petrelli, F Angelotti, C Croia… - Journal of asthma and …, 2019 - Taylor & Francis
Chronic urticaria (CU) is a mast cell-driven disease characterized by the development of
wheals, angioedema, or both for more than 6 weeks. The two major sub-types are chronic …

Clinical characterization of patients with chronic spontaneous urticaria according to anti‐TPO IgE levels

J Sánchez, A Sánchez… - Journal of immunology …, 2019 - Wiley Online Library
Background. Chronic spontaneous urticaria (CSU) is a heterogeneous disease with some
frequent comorbidities like autoimmune diseases, drug reactions, and inducible urticaria …

Histopathology of chronic spontaneous urticaria with occasional bruising lesions is not significantly different from urticaria with typical wheals

M Batista, R Calado, F Gil, JC Cardoso… - Journal of …, 2021 - Wiley Online Library
Background Chronic spontaneous urticaria (CSU) may occasionally exhibit long‐lasting
lesions with bruising, usually considered a hallmark of urticarial vasculitis (UV) …

What's New in the Treatment of Urticaria and Angioedema

DA Khan, E Kocatürk, A Bauer… - The Journal of Allergy and …, 2021 - Elsevier
Chronic urticaria and angioedema are diseases often managed by Allergy and Immunology
specialists. Recent international guidelines have outlined a stepwise approach to …