Traumatic brain injury (TBI) is one of the leading causes of death of young people in the
developed world. In the United States alone, 1.7 million traumatic events occur annually …

Abstract Traumatic Brain Injury (TBI) is the most frequent cause of death and disability in
young adults and children in the developed world, occurring in over 1.7 million persons and …

Traumatic axonal injury (TAI) is an important pathoanatomical subgroup of traumatic brain
injury (TBI) and a major driver of mortality and functional impairment. Experimental models …

The acute and long-term consequences of traumatic brain injury (TBI) have received
increased attention in recent years. In this Review, we discuss the neuropathology and …

Mild traumatic brain injury (TBI), which is defined as a head trauma resulting in a brief loss of
consciousness and/or alteration of mental state, is usually benign, but occasionally causes …

Eukaryotic cells have been confronted throughout their evolution with potentially lethal
plasma membrane injuries, including those caused by osmotic stress, by infection from …

Severe traumatic brain injury remains a major health-care problem worldwide. Although
major progress has been made in understanding of the pathophysiology of this injury, this …

Cysteine proteases continue to provide validated targets for treatment of human diseases. In
neurodegenerative disorders, multiple cysteine proteases provide targets for enzyme …

Introduction• Classifying TBI‐Clinical injury severity‐Focal injury or diffuse injury• Clinical
characteristics‐Coma, confusion and subacute impairments‐Imaging TBI‐Focal and diffuse …

Traumatic brain injury (TBI) results in significant disability due to cognitive deficits
particularly in attention, learning and memory, and higher-order executive functions. The …