Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in
the United States with an estimated 476,000 cases per year. While historically, the long-term …

Ixodes scapularis ticks transmit many pathogens that cause human disease, including
Borrelia burgdorferi. Acquired resistance to I. scapularis due to repeated tick exposure has …

Tick-borne diseases (TBDs) represent a growing burden for human and animal health
worldwide. Several approaches including the use of chemicals with repellency and …

Extracellular vesicles are thought to facilitate pathogen transmission from arthropods to
humans and other animals. Here, we reveal that pathogen spreading from arthropods to the …

During cutaneous tick attachment, the feeding cavity becomes a site of transmission for tick
salivary compounds and tick-borne pathogens. However, the immunological consequences …

Tick saliva contains a complex mixture of peptides and non-peptides that counteract their
hosts' hemostasis, immunity, and tissue-repair reactions. Recent transcriptomic studies have …

Ticks (Acari; Ixodidae) are the second most important vector for transmission of pathogens to
humans, livestock, and wildlife. Ticks as vectors for viruses have been reported many times …

The majority of ticks in the family Ixodidae secrete a substance anchoring their mouthparts to
the host skin. This substance is termed cement. It has adhesive properties and seals the …

The last three decades of research into tick salivary components have revealed several
proteins with important pharmacological and immunological activities. Two primary interests …