Myricetin (3, 5, 7, 3′, 4′, 5′-hexahydroxyflavone), a common dietary flavonoid, has been
reported for its roles in improving health due to various pharmacological activities, such as …

The complex and multifaceted nature of Alzheimer's disease has brought about a pressing
demand to develop ligands targeting multiple pathways to combat its outrageous …

Benzo [a] pyrene (B [a] P), a highly carcinogenic polycyclic aromatic hydrocarbon primarily
formed during incomplete organic matter combustion, undergoes a series of hepatic …

CYP2C8 is a crucial CYP isoform responsible for the metabolism of xenobiotics and
endogenous molecules. CYP2C8 converts arachidonic acid to epoxyeicosatrienoic acids …

In spite of unprecedented advances in modern cancer therapy, there is still a dearth of
targeted therapy to circumvent triple-negative breast cancer (TNBC). Paclitaxel is the front …

Ubiquitination is a crucial type of protein modification which helps to control substrate
degradation and maintain cell homeostasis. Recent studies suggest that ubiquitination and …

Crocetin is a promising phyto-based molecule to treat Alzheimer's disease (AD). The
chemical structure of crocetin is incongruent with various standard structural features of CNS …

Pinocembrin, a bioflavonoid, is extensively used in complementary/alternative medicine. It
turns out as a promising candidate against neurodegenerative diseases because of its …

Cannabidiol (CBD 1) is a nonpsychotic cannabinoid-based drug approved by the US FDA
for treating refractory epilepsy, namely, Lennox–Gastaut and Dravet syndrome. However, its …

The complex heterogenic environment of tumour mass often leads to drug resistance and
facilitate chemo insensitivity triggering more malignant phenotypes among cancer patients …