Endothelial–mesenchymal transition in atherosclerosis
C Souilhol, MC Harmsen, PC Evans… - Cardiovascular …, 2018 - academic.oup.com
Atherosclerosis is an inflammatory disease resulting in the hardening and thickening of the
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …
Integrins in mechanotransduction
A Katsumi, AW Orr, E Tzima, MA Schwartz - Journal of Biological Chemistry, 2004 - ASBMB
Mechanical forces are crucial to the regulation of cell and tissue morphology and function. At
the cellular level, forces influence cytoskeletal organization, gene expression, proliferation …
the cellular level, forces influence cytoskeletal organization, gene expression, proliferation …
Blood vessel organoids for development and disease
K Salewskij, JM Penninger - Circulation Research, 2023 - Am Heart Assoc
Despite enormous advances, cardiovascular disorders are still a major threat to global
health and are responsible for one-third of deaths worldwide. Research for new therapeutics …
health and are responsible for one-third of deaths worldwide. Research for new therapeutics …
Androgens and cardiovascular disease
PY Liu, AK Death, DJ Handelsman - Endocrine reviews, 2003 - academic.oup.com
Globally, cardiovascular disease will continue causing most human deaths for the
foreseeable future. The consistent gender gap in life span of approximately 5.6 yr in all …
foreseeable future. The consistent gender gap in life span of approximately 5.6 yr in all …
Spatial constraints control cell proliferation in tissues
SJ Streichan, CR Hoerner, T Schneidt… - Proceedings of the …, 2014 - National Acad Sciences
Control of cell proliferation is a fundamental aspect of tissue formation in development and
regeneration. Cells experience various spatial and mechanical constraints depending on …
regeneration. Cells experience various spatial and mechanical constraints depending on …
Intracranial arterial wall imaging using three‐dimensional high isotropic resolution black blood MRI at 3.0 Tesla
Purpose: To develop a high isotropic‐resolution sequence to evaluate intracranial vessels at
3.0 Tesla (T). Materials and Methods: Thirteen healthy volunteers and 4 patients with …
3.0 Tesla (T). Materials and Methods: Thirteen healthy volunteers and 4 patients with …
Residual strain effects on the stress field in a thick wall finite element model of the human carotid bifurcation
A Delfino, N Stergiopulos, JE Moore Jr… - Journal of biomechanics, 1997 - Elsevier
A three-dimensional finite element model of the carotid artery bifurcation was constructed in
order to determine the stress field and assess the modification of the stress field when …
order to determine the stress field and assess the modification of the stress field when …
The critical role of hemodynamics in the development of cerebral vascular disease: a review
Atherosclerosis and intracranial saccular aneurysms predictably localize in areas with
complex arterial geometries such as bifurcations and curvatures. These sites are …
complex arterial geometries such as bifurcations and curvatures. These sites are …
The effect of pressure-induced mechanical stretch on vascular wall differential gene expression
MA Anwar, J Shalhoub, CS Lim, MS Gohel… - Journal of vascular …, 2012 - karger.com
High blood pressure is responsible for the modulation of blood vessel morphology and
function. Arterial hypertension is considered to play a significant role in atherosclerotic …
function. Arterial hypertension is considered to play a significant role in atherosclerotic …
Vascular pathophysiology in response to increased heart rate
F Custodis, SH Schirmer, M Baumhäkel… - Journal of the American …, 2010 - jacc.org
This review summarizes the current literature and the open questions regarding the
physiology and pathophysiology of the mechanical effects of heart rate on the vessel wall …
physiology and pathophysiology of the mechanical effects of heart rate on the vessel wall …