Exploiting the mechanical effects of ultrasound for noninvasive therapy

MA O'Reilly - Science, 2024 - science.org
Focused ultrasound is a platform technology capable of eliciting a wide range of biological
responses with high spatial precision deep within the body. Although focused ultrasound is …

Current state of clinical ultrasound neuromodulation

E Matt, S Radjenovic, M Mitterwallner… - Frontiers in …, 2024 - frontiersin.org
Unmatched by other non-invasive brain stimulation techniques, transcranial ultrasound
(TUS) offers highly focal stimulation not only on the cortical surface but also in deep brain …

[HTML][HTML] Effects of different sonication parameters of theta burst transcranial ultrasound stimulation on human motor cortex

K Zeng, Z Li, X Xia, Z Wang, G Darmani, X Li, R Chen - Brain Stimulation, 2024 - Elsevier
Abstract Background Theta burst TUS (tbTUS) can induce increased cortical excitability in
human, but how different sonication parameters influence the effects are still unknown …

[HTML][HTML] Low-intensity focused ultrasound to the posterior insula reduces temporal summation of pain

A In, A Strohman, B Payne, W Legon - Brain stimulation, 2024 - Elsevier
Background The insula and dorsal anterior cingulate cortex (dACC) are core brain regions
involved in pain processing and central sensitization, a shared mechanism across various …

[HTML][HTML] Sustained reduction of essential tremor with low-power non-thermal transcranial focused ultrasound stimulations in humans

T Bancel, B Béranger, M Daniel, M Didier, M Santin… - Brain Stimulation, 2024 - Elsevier
Background Transcranial ultrasound stimulation (TUS) is a non-invasive brain stimulation
technique; when skull aberrations are compensated for, this technique allows, with …

Plasticity‐Induced Effects of Theta Burst Transcranial Ultrasound Stimulation in Parkinson's Disease

T Grippe, Y Shamli‐Oghli, G Darmani… - Movement …, 2024 - Wiley Online Library
Background Low‐intensity transcranial ultrasound stimulation (TUS) is a noninvasive brain
stimulation (NIBS) technique with high spatial specificity. Previous studies showed that TUS …

Holographic Ultrasound Modulates Neural Activity in a 1-Methyl-4-Phenyl-1, 2, 3, 6-Tetrahydropyridine-Induced Mouse Model of Parkinson's Disease

H Zhou, F Li, Z Lin, L Meng, D Chen, Q Zhang, L Niu - Research, 2024 - spj.science.org
Ultrasound (US) has emerged as a noninvasive neurostimulation method for motor control in
Parkinson's disease (PD). Previous in vivo US neuromodulation studies for PD were single …

Low-intensity focused ultrasound for human neuromodulation

W Legon, A Strohman - Nature Reviews Methods Primers, 2024 - nature.com
Low-intensity focused ultrasound (LIFU) is a potentially transformative form of human non-
invasive neuromodulation that provides millimetre-sized focal volumes combined with …

[HTML][HTML] Examination of the interaction of parameters for low-intensity focused ultrasound of the human motor cortex

A Ennasr, G Isaac, A Strohman, W Legon - Brain Stimulation, 2024 - Elsevier
Background Low-intensity focused ultrasound (LIFU) is a promising form of non-invasive
neuromodulation characterized by a rich parameter space that includes intensity, duration …

MR-guided focused ultrasound in movement disorders and beyond: Lessons learned and new frontiers

E Natera-Villalba, MA Ruiz-Yanzi… - Parkinsonism & Related …, 2024 - Elsevier
The development of MR-guided focused ultrasound (MRgFUS) has provided a new
therapeutic tool for neuropsychiatric disorders. In contrast to previously available …