Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …

Cardioprotection aims at infarct size reduction and improvement of clinical outcome from
myocardial infarction. The translation of cardioprotection from preclinical and promising …

BACKGROUND: Patients with a history of hypertension have elevated inflammation and a
worse prognosis after acute myocardial infarction (AMI). Regulatory T cells (Tregs) are …

Optimal risk assessment for primary prevention remains highly challenging. Recent
registries have highlighted major discrepancies between guidelines and daily practice …

Myocardial infarction (MI) remains a leading cause of morbidity and mortality. In
atherothrombotic MI (ST-elevation MI and type 1 non-ST-elevation MI), coronary artery …

Cardiac magnetic resonance (CMR) imaging allows comprehensive assessment of
myocardial function and tissue characterization in a single examination after acute ST …

Why can we still not translate preclinical research to clinical treatments for acute strokes?
Despite> 1000 successful preclinical studies, drugs, and concepts for acute stroke, only two …

Calcium overload is the key trigger in cardiac microvascular ischemia–reperfusion (I/R)
injury, and calreticulin (CRT) is a calcium buffering protein located in the endoplasmic …

Acute myocardial infarction (AMI) is one of the primary causes of death worldwide, with a
high incidence and mortality rate. Assessment of the infarcted and surviving myocardium …

Aims Cardiovascular disease and cancer share common pathogenesis and risk factors.
Coronary microvascular dysfunction (CMD), reflecting impaired coronary microvascular …