The gene ontology knowledgebase in 2023

SA Aleksander, J Balhoff, S Carbon, JM Cherry… - Genetics, 2023 - academic.oup.com
Abstract The Gene Ontology (GO) knowledgebase (http://geneontology. org) is a
comprehensive resource concerning the functions of genes and gene products (proteins …

Network pharmacology approaches for research of Traditional Chinese Medicines

LI Xiang, LIU Ziqi, L Jie, C Qian, LU Xiaoyan… - Chinese Journal of …, 2023 - Elsevier
Pharmacodynamics material basis and effective mechanisms are the two main issues to
decipher the mechnisms of action of Traditional Chinese medicines (TCMs) for the treatment …

[PDF][PDF] The gene ontology knowledgebase in 2023

D Ebert, M Feuermann, P Gaudet, NL Harris, DP Hill… - Genetics, 2023 - crick.figshare.com
Abstract The Gene Ontology (GO) knowledgebase (http://geneontology. org) is a
comprehensive resource concerning the functions of genes and gene products (proteins …

Ensembl 2023

FJ Martin, MR Amode, A Aneja… - Nucleic acids …, 2023 - academic.oup.com
Abstract Ensembl (https://www. ensembl. org) has produced high-quality genomic resources
for vertebrates and model organisms for more than twenty years. During that time, our …

[HTML][HTML] Pan-cancer proteogenomics connects oncogenic drivers to functional states

Y Li, E Porta-Pardo, C Tokheim, MH Bailey, TM Yaron… - Cell, 2023 - cell.com
Cancer driver events refer to key genetic aberrations that drive oncogenesis; however, their
exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan …

SIGNOR 3.0, the SIGnaling network open resource 3.0: 2022 update

P Lo Surdo, M Iannuccelli, S Contino… - Nucleic acids …, 2023 - academic.oup.com
Abstract The SIGnaling Network Open Resource (SIGNOR 3.0, https://signor. uniroma2. it) is
a public repository that captures causal information and represents it according to an 'activity …

The 2022 Nucleic Acids Research database issue and the online molecular biology database collection

DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation

CY Lee, D Hubrich, JK Varga, C Schäfer… - Molecular Systems …, 2024 - embopress.org
Structural resolution of protein interactions enables mechanistic and functional studies as
well as interpretation of disease variants. However, structural data is still missing for most …

Deciphering the impact of genomic variation on function

Code of Conduct Committee (alphabetical by last name … - Nature, 2024 - nature.com
Our genomes influence nearly every aspect of human biology—from molecular and cellular
functions to phenotypes in health and disease. Studying the differences in DNA sequence …

PED in 2024: improving the community deposition of structural ensembles for intrinsically disordered proteins

H Ghafouri, T Lazar, A Del Conte… - Nucleic acids …, 2024 - academic.oup.com
Abstract The Protein Ensemble Database (PED)(URL: https://proteinensemble. org) is the
primary resource for depositing structural ensembles of intrinsically disordered proteins. This …