Glycerol utilization as a carbohydrate source by Borreliella burgdorferi, the Lyme disease
spirochete, is critical for its successful colonization and persistence in the tick vector. The …

The genus Borrelia comprises two major groups of spirochetes with at least 43 validated
species. The first group contains Borrelia species within the Borrelia burgdorferi sensu lato …

Introduction Lyme disease, the most common tick-borne infectious disease in the US, is
caused by a spirochetal pathogen Borrelia burgdorferi (Bb). Distinct host responses are …

Borrelia burgdorferi, the Lyme disease pathogen causes persistent infection by evading the
host immune response. Differential expression of the surface-exposed lipoprotein VlsE that …

Lyme disease pathogen Borrelia burgdorferi, switches carbohydrate utilization while
transmitting between two disparate hosts, an Ixodes tick vector and a mammalian host. The …

The Peptidoglycan (PG) cell wall of the Lyme disease (LD) spirochete, Borrelia burgdorferi
(Bb), contributes to structural and morphological integrity of Bb; is a persistent antigen in LD …

During the natural enzootic life cycle of Borrelia burgdorferi (also known as Borreliella
burgdorferi), the bacteria must sense conditions within the vertebrate and arthropod and …

Transformation techniques used to genetically manipulate Borrelia burgdorferi, the agent of
Lyme disease, play a critical role in generating mutants that facilitate analyses of the role of …

Borrelia burgdorferi, the agent of Lyme disease, is transmitted to humans and other
mammalian hosts via the bite of infected Ixodes scapularis ticks. B. burgdorferi exhibits …

Borrelia burgdorferi (Bb), the causative agent of Lyme disease, has a compact genome with
limited metabolic capabilities and is therefore a highly host-adapted pathogen with …