Manipulating neutrophil degranulation as a bacterial virulence strategy
KR Eichelberger, WE Goldman - PLoS pathogens, 2020 - journals.plos.org
Armed with an arsenal of antimicrobial mechanisms, neutrophils are among the first innate
immune cells recruited to the site of bacterial infection. Neutrophils utilize both oxidative and …
immune cells recruited to the site of bacterial infection. Neutrophils utilize both oxidative and …
Yersinia interactions with regulated cell death pathways
KW Chen, IE Brodsky - Current Opinion in Microbiology, 2023 - Elsevier
Cell death in response to infection is conserved across all kingdoms of life. In metazoans,
cell death upon bacterial infection is primarily carried out by the cysteine and aspartate …
cell death upon bacterial infection is primarily carried out by the cysteine and aspartate …
Type 3 secretion system induced leukotriene B4 synthesis by leukocytes is actively inhibited by Yersinia pestis to evade early immune recognition
A Brady, KR Sheneman, AR Pulsifer, SL Price… - Plos …, 2024 - journals.plos.org
Subverting the host immune response to inhibit inflammation is a key virulence strategy of
Yersinia pestis. The inflammatory cascade is tightly controlled via the sequential action of …
Yersinia pestis. The inflammatory cascade is tightly controlled via the sequential action of …
[HTML][HTML] Pan-genomics, drug candidate mining and ADMET profiling of natural product inhibitors screened against Yersinia pseudotuberculosis
Yersinia pseudotuberculosis belongs to the family Enterobacteriaceae and is responsible for
scarlatinoid fever, food poisoning, post-infectious complications like erythema …
scarlatinoid fever, food poisoning, post-infectious complications like erythema …
Pathogenicity and virulence of Yersinia
JA Seabaugh, DM Anderson - Virulence, 2024 - Taylor & Francis
The genus Yersinia includes human, animal, insect, and plant pathogens as well as many
symbionts and harmless bacteria. Within this genus are Yersinia enterocolitica and the …
symbionts and harmless bacteria. Within this genus are Yersinia enterocolitica and the …
Host manipulation by bacterial type III and type IV secretion system effector proteases
Proteases are powerful enzymes, which cleave peptide bonds, leading most of the time to
irreversible fragmentation or degradation of their substrates. Therefore they control many …
irreversible fragmentation or degradation of their substrates. Therefore they control many …
Redundant and cooperative roles for Yersinia pestis yop effectors in the inhibition of human neutrophil exocytic responses revealed by gain-of-function approach
AR Pulsifer, A Vashishta, SA Reeves… - Infection and …, 2020 - Am Soc Microbiol
Yersinia pestis causes a rapid, lethal disease referred to as plague. Y. pestis actively inhibits
the innate immune system to generate a noninflammatory environment during early stages …
the innate immune system to generate a noninflammatory environment during early stages …
Mapping quantitative trait loci related to nodule number in soybean (Glycine max (L.) Merr.) in response to the Sinorhizobium (Ensifer) fredii HH103 NopT type III …
Y Liu, M Sun, Q Chen, D Xin, X Sun - Journal of Plant Interactions, 2021 - Taylor & Francis
Type III effectors play a vital role in the establishment of symbiosis. In this study, positive and
negative effects of NopT on nodulation were detected in 30 soybean germplasms. The …
negative effects of NopT on nodulation were detected in 30 soybean germplasms. The …
Advances and challenges in studying type III secretion effectors of attaching and effacing pathogens
Outbreaks of the diarrhoeal disease caused by enteropathogenic Escherichia coli (EPEC)
and enterohaemorrhagic E. coli (EHEC) present a significant burden to public health in …
and enterohaemorrhagic E. coli (EHEC) present a significant burden to public health in …
[HTML][HTML] Yersinia pestis escapes entrapment in thrombi by targeting platelet function
SG Palace, O Vitseva, MK Proulx, JE Freedman… - Journal of Thrombosis …, 2020 - Elsevier
Background Platelets are classically recognized for their role in hemostasis and thrombosis.
Recent work has demonstrated that platelets can also execute a variety of immune functions …
Recent work has demonstrated that platelets can also execute a variety of immune functions …