Metals at the Host–Fungal Pathogen Battleground
R Garg, MS David, S Yang… - Annual Review of …, 2024 - annualreviews.org
Fungal infections continue to represent a major threat to public health, particularly with the
emergence of multidrug-resistant fungal pathogens. As part of the innate immune response …
emergence of multidrug-resistant fungal pathogens. As part of the innate immune response …
Novel avenues for identification of new antifungal drugs and current challenges
J Jampilek - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Some of the fungi have become pathogenic to humans, and these opportunistic
pathogens are able to cause severe systemic mycoses. Areas covered The number of …
pathogens are able to cause severe systemic mycoses. Areas covered The number of …
[HTML][HTML] Physiological and transcriptional profiling of surfactin exerted antifungal effect against Candida albicans
Given the risk of Candida albicans overgrowth in the gut, novel complementary therapies
should be developed to reduce fungal dominancy. This study highlights the antifungal …
should be developed to reduce fungal dominancy. This study highlights the antifungal …
Calcitermin-Loaded Smart Gels Activity against Candida albicans: A Preliminary In Vitro Study
D Bellotti, M D'accolti, W Pula, N Huang, F Simeliere… - Gels, 2023 - mdpi.com
Calcitermin is an antimicrobial peptide of 15 amino acids found in human nasal fluid
characterized by antifungal and antibacterial properties. Candida albicans is the most …
characterized by antifungal and antibacterial properties. Candida albicans is the most …
Zn2+ and Cu2+ Interaction with the Recognition Interface of ACE2 for SARS-CoV-2 Spike Protein
The spike protein (S) of SARS-CoV-2 is able to bind to the human angiotensin-converting
enzyme 2 (ACE2) receptor with a much higher affinity compared to other coronaviruses. The …
enzyme 2 (ACE2) receptor with a much higher affinity compared to other coronaviruses. The …
[HTML][HTML] Investigation of metal interactions with YrpE protein of Bacillus subtilis by a polyhistidine peptide model
D Bellotti, S Leveraro, A Hecel, M Remelli - Analytical Biochemistry, 2023 - Elsevier
The use of model peptides that can simulate the behaviour of a protein domain is a very
successful analytical method to study the metal coordination sites in biological systems …
successful analytical method to study the metal coordination sites in biological systems …
Toxic and essential metals in human health and disease 2021
JO Aaseth - Biomolecules, 2022 - mdpi.com
The Special Issue of Biomolecules called “Toxic and Essential Metals in Human Health and
Disease 2021” represents a follow-up of the previous Special Issue with the name of “Toxic …
Disease 2021” represents a follow-up of the previous Special Issue with the name of “Toxic …
Metal coordination governs the antimicrobial efficacy of calcitermin derivatives
S Leveraro, K Garstka, P Śliwka, T Janek… - Dalton …, 2024 - pubs.rsc.org
Antimicrobial peptides are promising alternatives to classical antibiotics. Their microbicidal
activity can arise from different mechanisms, one of which is known as nutritional immunity …
activity can arise from different mechanisms, one of which is known as nutritional immunity …
CDF family of zinc transporters ZRC-1, MSC-2, and ZRG-17 are involved in survival at high zinc conditions, vegetative development, and cellulase utilization in …
S Ngiimei D, R Tamuli - Journal of Biosciences, 2024 - Springer
The cation diffusion facilitator (CDF) family of zinc transporters plays a crucial role in zinc
homeostasis in eukaryotes, including fungi. Here, we investigated the cell functions and …
homeostasis in eukaryotes, including fungi. Here, we investigated the cell functions and …
Metal–protein solution interactions investigated using model systems: Thermodynamic and spectroscopic methods
D Bellotti, S Leveraro, M Remelli - Methods in Enzymology, 2023 - Elsevier
The first-row D-block metal ions are essential for the physiology of living organisms,
functioning as cofactors in metalloproteins or structural components for enzymes: almost half …
functioning as cofactors in metalloproteins or structural components for enzymes: almost half …