Patients with cardiovascular disease and, namely, heart failure are more susceptible to
coronavirus disease 2019 (COVID‐19) and have a more severe clinical course once …

Heart failure (HF) remains the most common cause of death and disability, and a major
economic burden, in industrialized nations. Physiological, pharmacological, and clinical …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China,
at the end of 2019, and there are currently no specific antiviral treatments or vaccines …

SARS-CoV-2 is a novel virus of the Coronaviridiae family that represents a major global
health issue. Mechanisms implicated in virus/host cells interaction are central for cell …

In light of the outbreak of the 2019 novel coronavirus disease (COVID-19), the international
scientific community has joined forces to develop effective treatment strategies. The …

The renin–angiotensin system (RAS) has pivotal roles in the regulation of normal physiology
and the pathogenesis of cardiovascular disease. Angiotensin-converting enzyme (ACE) 2 …

Recent advances have improved our understanding of the renin‐angiotensin system (RAS).
These have included the recognition that angiotensin (A ng)‐(1‐7) is a biologically active …

Angiotensin-converting enzyme type 2 (ACE2) is a pivotal component of the renin–
angiotensin system, promoting the conversion of angiotensin II (Ang-II) to Ang-(1-7). We …

Abstract The Renin Angiotensin System (RAS) is a pivotal physiological regulator of heart
and kidney homeostasis, but also plays an important role in the pathophysiology of heart …

The renin–angiotensin–aldosterone system (RAAS) is a key regulator of systemic blood
pressure and renal function and a key player in renal and cardiovascular disease. However …