Background: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous
system characterized by demyelination and axonal loss. The etiology of MS is unknown; …

Multiple sclerosis is one of the most common causes of chronic neurological disability
beginning in early to middle adult life. Multiple sclerosis is idiopathic in nature, yet …

Multiple sclerosis (MS) is a central nervous system chronic inflammatory disease that is
characterized by an extensive and complex immune response. Scientific advances have …

Multiple sclerosis (MS) is the most common autoimmune disease affecting the central
nervous system. It is characterized by auto-reactive T cells that induce demyelination and …

Neurological disorders affect the nervous system. Biochemical, structural, or electrical
abnormalities in the spinal cord, brain, or other nerves lead to different symptoms, including …

Oligodendrocytes are myelin-forming glia that ensheath the axons of neurons in the CNS.
Recent studies have revealed that Wnt/β-catenin signaling plays important roles in …

Demyelinating diseases, such as multiple sclerosis, are characterized by inflammatory
demyelination and neurodegeneration of the central nervous system. Therapeutic strategies …

Background: Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous
system in which a higher oxidative stress may contribute to its pathogenesis. The aim of this …

Cyclotides represent a new class of natural plant compounds, which could be considered
ideal “template” molecules for drug design. Their structure is characterized by a circular …

Repulsive guidance molecule A (RGMa) is a potent inhibitor of neuronal regeneration and a
regulator of cell death, and it plays a role in multiple sclerosis (MS). In autopsy material from …