Gangliosides are expressed in the outer leaflet of the plasma membrane of the cells of all
vertebrates and are particularly abundant in the nervous system. Ganglioside metabolism is …

Gangliosides (sialic acid-containing glycosphingolipids) are abundant in neurons of all
animal species and play important roles in many cell physiological processes, including …

The present study determines the affinity of cholera toxin for the ganglioside series GM1,
GM2, GM3, GD1A, GD1B, GT1B, asialo GM1, globotriosyl ceramide, and lactosyl ceramide …

Cholera toxin (Ctx) from Vibrio cholerae and its closely related homologue, heat-labile
enterotoxin (Etx) from Escherichia coli have become superb tools for illuminating pathways …

The complex of cholera toxin and ganglioside GM1 is one of the highest affinity protein−
carbohydrate interactions known. Herein, the GM1 pentasaccharide is dissected into smaller …

Several studies have successfully employed GM1 ganglioside to treat animal models of
Parkinson's disease (PD), suggesting involvement of this ganglioside in PD etiology. We …

The specific recognition reaction between cholera toxin (ChTo) and the gangliosideGmi was
investigated in situ on planar supported lipid layers using simultaneous surface plasmon …

This book provides basic principles of multivalent interactions found in biological systems as
well as an up-to-date and thorough coverage in design concepts, syntheses, and biological …

The primary virulence factors of many pathogenic bacteria are secreted protein toxins which
bind to glycolipid receptors on host cell surfaces. The binding specificities of three such …

Gangliosides in the outer leaflet of the plasma membrane of eukaryotic cells are essential for
many cellular functions and pathogenic interactions. How gangliosides are dynamically …