Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …

Piper species are aromatic plants used as spices in the kitchen, but their secondary
metabolites have also shown biological effects on human health. These plants are rich in …

Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

Different animal and human studies from last two decades in the case of Parkinson's
disease (PD) have concentrated on oxidative stress due to increased inflammation and …

Neuroinflammation is one of the main mechanisms involved in the progression of
neurodegeneration. The activation of microglia is the main feature of neuroinflammation …

Inflammation plays important roles in the progress of neurodegenerative diseases, such as
Parkinson's disease and Alzheimer's disease. Microglia is responsible for the homeostasis …

In 2020, a novel strain of coronavirus (COVID-19) has led to a significant morbidity and
mortality worldwide. As of the date of this writing, a total of 116 M cases has been diagnosed …

One of the biggest challenges in drug development for Alzheimer's disease (AD) is how to
effectively remove deposits of amyloid-beta (Aβ). Recently, the relationship between …

Piperlongumine (PL) is an alkaloid from Piper longum L. with anti-inflammatory and
antitumor properties. Numerous studies have focused on its antitumor effect. However, the …

Deregulation of glycolysis is a common phenomenon in human non-small cell lung cancer
(NSCLC). In the present study, we reported the natural compound, piperlongumine, has a …