Evaluation of skin absorption of drugs from topical and transdermal formulations
ALM Ruela, AG Perissinato, MES Lino… - Brazilian journal of …, 2016 - SciELO Brasil
The skin barrier function has been attributed to the stratum corneum and represents a major
challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a …
challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a …
Approaches for breaking the barriers of drug permeation through transdermal drug delivery
Transdermal drug delivery system (TDDS) utilizes the skin as executable route for drug
administration but the foremost barrier against drug permeability is the stratum corneum and …
administration but the foremost barrier against drug permeability is the stratum corneum and …
A compliant ionic adhesive electrode with ultralow bioelectronic impedance
Simultaneous implementation of high signal‐to‐noise ratio (SNR) but low crosstalk is of
great importance for weak surface electromyography (sEMG) signals when precisely driving …
great importance for weak surface electromyography (sEMG) signals when precisely driving …
Design principles of ionic liquids for transdermal drug delivery
Ionic liquids (ILs) and deep eutectic solvents have shown great promise in drug delivery
applications. Choline‐based ILs, in particular choline and geranic acid (CAGE), have been …
applications. Choline‐based ILs, in particular choline and geranic acid (CAGE), have been …
Using molecular simulation to understand the skin barrier
Skin's effectiveness as a barrier to permeation of water and other chemicals rests almost
entirely in the outermost layer of the epidermis, the stratum corneum (SC), which consists of …
entirely in the outermost layer of the epidermis, the stratum corneum (SC), which consists of …
[HTML][HTML] Comparison between Franz diffusion cell and a novel micro-physiological system for in vitro penetration assay using different skin models
In vitro diffusive models are an important tool to screen the penetration ability of active
ingredients in various formulations. A reliable assessment of skin penetration enhancing …
ingredients in various formulations. A reliable assessment of skin penetration enhancing …
Recent advances in nanomaterials for dermal and transdermal applications
A Zoabi, E Touitou, K Margulis - Colloids and Interfaces, 2021 - mdpi.com
The stratum corneum, the most superficial layer of the skin, protects the body against
environmental hazards and presents a highly selective barrier for the passage of drugs and …
environmental hazards and presents a highly selective barrier for the passage of drugs and …
[HTML][HTML] Molecular simulation of nonfacilitated membrane permeation
E Awoonor-Williams, CN Rowley - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
This is a review. Non-electrolytic compounds typically cross cell membranes by passive
diffusion. The rate of permeation is dependent on the chemical properties of the solute and …
diffusion. The rate of permeation is dependent on the chemical properties of the solute and …
Quantitative structure-skin permeability relationships
This paper reviews in silico models currently available for the prediction of skin permeability.
A comprehensive discussion on the developed methods is presented, focusing on …
A comprehensive discussion on the developed methods is presented, focusing on …
Molecular dynamics simulation study of permeation of molecules through skin lipid bilayer
Stratum Corneum (SC), the outermost layer of skin, is mainly responsible for skin's barrier
function. The complex lipid matrix of SC determines these barrier properties. In this study …
function. The complex lipid matrix of SC determines these barrier properties. In this study …