Conceptualizing outcomes for use with the Consolidated Framework for Implementation Research (CFIR): the CFIR Outcomes Addendum

LJ Damschroder, CM Reardon… - Implementation …, 2022 - Springer
Background The challenges of implementing evidence-based innovations (EBIs) are widely
recognized among practitioners and researchers. Context, broadly defined as everything …

Enabling technologies for personalized and precision medicine

D Ho, SR Quake, ERB McCabe, WJ Chng… - Trends in …, 2020 - cell.com
Individualizing patient treatment is a core objective of the medical field. Reaching this
objective has been elusive owing to the complex set of factors contributing to both disease …

[HTML][HTML] Integrating genomics into healthcare: a global responsibility

Z Stark, L Dolman, TA Manolio, B Ozenberger… - The American Journal of …, 2019 - cell.com
Genomic sequencing is rapidly transitioning into clinical practice, and implementation into
healthcare systems has been supported by substantial government investment, totaling over …

[HTML][HTML] Meeting the challenges of implementing rapid genomic testing in acute pediatric care

Z Stark, S Lunke, GR Brett, NB Tan, R Stapleton… - Genetics in …, 2018 - Elsevier
Purpose The purpose of the study was to implement and prospectively evaluate the
outcomes of a rapid genomic diagnosis program at two pediatric tertiary centers. Methods …

[HTML][HTML] Defining and achieving health equity in genomic medicine

S Jooma, MJ Hahn, LA Hindorff, VL Bonham - Ethnicity & disease, 2019 - ncbi.nlm.nih.gov
The potential of genomics to improve health comes with the peril that the benefits will not be
equitably available to all populations. Existing health disparities can be exacerbated if the …

Pharmacogenomic testing to support prescribing in primary care: a structured review of implementation models

J Hayward, J McDermott, N Qureshi… - …, 2021 - Taylor & Francis
The application of pharmacogenomics could meaningfully contribute toward medicines
optimization within primary care. This review identified 13 studies describing eight …

What is the power of a genomic multidisciplinary team approach? A systematic review of implementation and sustainability

A Ma, R O'Shea, L Wedd, C Wong… - European Journal of …, 2024 - nature.com
Due to the increasing complexity of genomic data interpretation, and need for close
collaboration with clinical, laboratory, and research expertise, genomics often requires a …

Building evidence and measuring clinical outcomes for genomic medicine

JF Peterson, DM Roden, LA Orlando, AH Ramirez… - The Lancet, 2019 - thelancet.com
Human genomic sequencing has potential diagnostic, prognostic, and therapeutic value
across a wide breadth of clinical disciplines. One barrier to widespread adoption is the …

[HTML][HTML] Attitudes and practices of Australian nephrologists toward implementation of clinical genomics

K Jayasinghe, C Quinlan, AJ Mallett, PG Kerr… - Kidney international …, 2021 - Elsevier
Introduction Genomic testing is becoming widely available as a diagnostic tool, although
widespread implementation is not yet established in nephrology. Methods An anonymous …

A roadmap for global acceleration of genomics integration across nursing

E Tonkin, KA Calzone, L Badzek… - Journal of Nursing …, 2020 - Wiley Online Library
Purpose The changes needed to accelerate integration of genomics across nursing are
complex, with significant challenges faced globally. Common themes lend themselves to a …