Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?
With the aging population, prevalence of neurodegenerative diseases is increasing, thus
placing a growing burden on individuals and the whole society. However, individual rates of …
placing a growing burden on individuals and the whole society. However, individual rates of …
Roles of physical exercise in neurodegeneration: reversal of epigenetic clock
M Xu, JY Zhu, XD Liu, MY Luo, NJ Xu - Translational Neurodegeneration, 2021 - Springer
The epigenetic clock is defined by the DNA methylation (DNAm) level and has been
extensively applied to distinguish biological age from chronological age. Aging-related …
extensively applied to distinguish biological age from chronological age. Aging-related …
Mind the gap: Performance metric evaluation in brain‐age prediction
Estimating age based on neuroimaging‐derived data has become a popular approach to
developing markers for brain integrity and health. While a variety of machine‐learning …
developing markers for brain integrity and health. While a variety of machine‐learning …
[HTML][HTML] Predicting brain age with complex networks: From adolescence to adulthood
In recent years, several studies have demonstrated that machine learning and deep learning
systems can be very useful to accurately predict brain age. In this work, we propose a novel …
systems can be very useful to accurately predict brain age. In this work, we propose a novel …
BrainAGE, brain health, and mental disorders: A systematic review
The imaging-based method of brainAGE aims to characterize an individual's vulnerability to
age-related brain changes. The present study systematically reviewed brainAGE findings in …
age-related brain changes. The present study systematically reviewed brainAGE findings in …
A neuroimaging signature of cognitive aging from whole‐brain functional connectivity
Cognitive decline is amongst one of the most commonly reported complaints during normal
aging. Despite evidence that age and cognition are linked with similar neural correlates, no …
aging. Despite evidence that age and cognition are linked with similar neural correlates, no …
Premature brain aging in humans exposed to maternal nutrient restriction during early gestation
Background Prenatal exposure to undernutrition is widespread in both developing and
industrialized countries, causing irreversible damage to the developing brain, resulting in …
industrialized countries, causing irreversible damage to the developing brain, resulting in …
Neuroimaging-based brain age estimation: A promising personalized biomarker in neuropsychiatry
D Sone, I Beheshti - Journal of Personalized Medicine, 2022 - mdpi.com
It is now possible to estimate an individual's brain age via brain scans and machine-learning
models. This validated technique has opened up new avenues for addressing clinical …
models. This validated technique has opened up new avenues for addressing clinical …
[HTML][HTML] Prominent health problems, socioeconomic deprivation, and higher brain age in lonely and isolated individuals: A population-based study
Loneliness is linked to increased risk for Alzheimer's disease, but little is known about
factors potentially contributing to adverse brain health in lonely individuals. In this study, we …
factors potentially contributing to adverse brain health in lonely individuals. In this study, we …
Geroscience-centric perspective for geriatric psychiatry: integrating aging biology with geriatric mental health research
The geroscience hypothesis asserts that physiological aging is caused by a small number of
biological pathways. Despite the explosion of geroscience research over the past couple of …
biological pathways. Despite the explosion of geroscience research over the past couple of …