Vascular remodeling after ischemic stroke: mechanisms and therapeutic potentials
The brain vasculature has been increasingly recognized as a key player that directs brain
development, regulates homeostasis, and contributes to pathological processes. Following …
development, regulates homeostasis, and contributes to pathological processes. Following …
Impact of microRNAs on ischemic stroke: from pre-to post-disease
G Li, KC Morris-Blanco, MS Lopez, T Yang… - Progress in …, 2018 - Elsevier
Stroke is the number one cause of neurological dysfunction in adults and has a heavy
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …
Mapping the fine-scale organization and plasticity of the brain vasculature
The cerebral vasculature is a dense network of arteries, capillaries, and veins. Quantifying
variations of the vascular organization across individuals, brain regions, or disease models …
variations of the vascular organization across individuals, brain regions, or disease models …
Angiogenesis after ischemic stroke
J Fang, Z Wang, C Miao - Acta Pharmacologica Sinica, 2023 - nature.com
Owing to its high disability and mortality rates, stroke has been the second leading cause of
death worldwide. Since the pathological mechanisms of stroke are not fully understood …
death worldwide. Since the pathological mechanisms of stroke are not fully understood …
Functional dissection of astrocyte-secreted proteins: Implications in brain health and diseases
Astrocytes, which are homeostatic cells of the central nervous system (CNS), display
remarkable heterogeneity in their morphology and function. Besides their physical and …
remarkable heterogeneity in their morphology and function. Besides their physical and …
MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain
Angiogenesis and neurogenesis are crucial processes for brain tissue repair and
remodeling after brain injury. Current study shows that microRNA-210 (miR-210) promotes …
remodeling after brain injury. Current study shows that microRNA-210 (miR-210) promotes …
Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke
R Rust, L Grönnert, C Gantner… - Proceedings of the …, 2019 - National Acad Sciences
Stroke is a major cause of serious disability due to the brain's limited capacity to regenerate
damaged tissue and neuronal circuits. After ischemic injury, a multiphasic degenerative and …
damaged tissue and neuronal circuits. After ischemic injury, a multiphasic degenerative and …
MicroRNA-126 regulates angiogenesis and neurogenesis in a mouse model of focal cerebral ischemia
M Qu, J Pan, L Wang, P Zhou, Y Song, S Wang… - … Therapy-Nucleic Acids, 2019 - cell.com
Studies demonstrate that microRNA-126 plays a critical role in promoting angiogenesis.
However, its effects on angiogenesis following ischemic stroke are unclear. Here, we …
However, its effects on angiogenesis following ischemic stroke are unclear. Here, we …
Rehabilitation and plasticity following stroke: insights from rodent models
M Caleo - Neuroscience, 2015 - Elsevier
Ischemic injuries within the motor cortex result in functional deficits that may profoundly
impact activities of daily living in patients. Current rehabilitation protocols achieve only …
impact activities of daily living in patients. Current rehabilitation protocols achieve only …
Pro‐and antiangiogenic therapies: current status and clinical implications
R Rust, C Gantner, ME Schwab - The FASEB Journal, 2019 - Wiley Online Library
Blood vessels nurture every part of the human body. Consequently, abnormalities in the
vasculature are closely associated with a variety of diseases, including cerebral stroke, heart …
vasculature are closely associated with a variety of diseases, including cerebral stroke, heart …