Molecular networks in Network Medicine: Development and applications

EK Silverman, HHHW Schmidt… - … Systems Biology and …, 2020 - Wiley Online Library
Network Medicine applies network science approaches to investigate disease
pathogenesis. Many different analytical methods have been used to infer relevant molecular …

Epigenetic-sensitive pathways in personalized therapy of major cardiovascular diseases

C Schiano, G Benincasa, M Franzese… - Pharmacology & …, 2020 - Elsevier
The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …

Precision medicine in distinct heart failure phenotypes: focus on clinical epigenetics

C Napoli, G Benincasa, F Donatelli, G Ambrosio - American heart journal, 2020 - Elsevier
Heart failure (HF) management is challenging due to high clinical heterogeneity of this
disease which makes patients responding differently to evidence-based standard therapy …

Radiogenomics and artificial intelligence approaches applied to cardiac computed tomography angiography and cardiac magnetic resonance for precision medicine …

T Infante, C Cavaliere, B Punzo, V Grimaldi… - Circulation …, 2021 - Am Heart Assoc
The risk of coronary heart disease (CHD) clinical manifestations and patient management is
estimated according to risk scores accounting multifactorial risk factors, thus failing to cover …

Multi-modality multi-scale cardiovascular disease subtypes classification using Raman image and medical history

B Yu, H Chen, C Jia, H Zhou, L Cong, X Li… - Expert Systems with …, 2023 - Elsevier
Raman spectroscopy (RS) has been widely used for disease diagnosis, eg, cardiovascular
disease (CVD), owing to its efficiency and component-specific testing capabilities. A series …

[HTML][HTML] Recent trends in artificial intelligence-assisted coronary atherosclerotic plaque characterization

A Gudigar, S Nayak, J Samanth… - International journal of …, 2021 - mdpi.com
Coronary artery disease is a major cause of morbidity and mortality worldwide. Its underlying
histopathology is the atherosclerotic plaque, which comprises lipid, fibrous and—when …

Network medicine: a clinical approach for precision medicine and personalized therapy in coronary heart disease

T Infante, L Del Viscovo, ML De Rimini… - … of Atherosclerosis and …, 2020 - jstage.jst.go.jp
Early identification of coronary atherosclerotic pathogenic mechanisms is useful for
predicting the risk of coronary heart disease (CHD) and future cardiac events. Epigenome …

Quantum machine learning‐based framework to detect heart failures in Healthcare 4.0

M Munshi, R Gupta, NK Jadav… - Software: Practice …, 2024 - Wiley Online Library
Quantum machine learning (QML) is an emerging field that combines the power of quantum
computing with machine learning (ML) techniques to solve complex problems. In recent …

Statins for the primary prevention of coronary heart disease

M Li, X Wang, X Li, H Chen, Y Hu… - BioMed Research …, 2019 - Wiley Online Library
Object. The purpose of this study was to fully assess the role of statins in the primary
prevention of coronary heart disease (CHD). Methods. We searched six databases …

[HTML][HTML] Evidence of association of circulating epigenetic-sensitive biomarkers with suspected coronary heart disease evaluated by Cardiac Computed Tomography

T Infante, E Forte, C Schiano, B Punzo, F Cademartiri… - PLoS …, 2019 - journals.plos.org
Circulating biomarkers available in clinical practice do not allow to stratify patients with
coronary heart disease (CHD) prior the onset of a clinically relevant event. We evaluated the …