Light modulates glucose metabolism by a retina-hypothalamus-brown adipose tissue axis
Public health studies indicate that artificial light is a high-risk factor for metabolic disorders.
However, the neural mechanism underlying metabolic modulation by light remains elusive …
However, the neural mechanism underlying metabolic modulation by light remains elusive …
[HTML][HTML] Melanopsin retinal ganglion cells mediate light-promoted brain development
J Hu, Y Shi, J Zhang, X Huang, Q Wang, H Zhao… - Cell, 2022 - cell.com
During development, melanopsin-expressing intrinsically photosensitive retinal ganglion
cells (ipRGCs) become light sensitive much earlier than rods and cones. IpRGCs project to …
cells (ipRGCs) become light sensitive much earlier than rods and cones. IpRGCs project to …
Zona incerta GABAergic neurons integrate prey-related sensory signals and induce an appetitive drive to promote hunting
The neural substrates for predatory hunting, an evolutionarily conserved appetitive behavior,
remain largely undefined. Photoactivation of zona incerta (ZI) GABAergic neurons strongly …
remain largely undefined. Photoactivation of zona incerta (ZI) GABAergic neurons strongly …
[HTML][HTML] A visual circuit related to the nucleus reuniens for the spatial-memory-promoting effects of light treatment
X Huang, P Huang, L Huang, Z Hu, X Liu, J Shen, Y Xi… - Neuron, 2021 - cell.com
Light exerts profound effects on cognitive functions across species, including humans.
However, the neuronal mechanisms underlying the effects of light on cognitive functions are …
However, the neuronal mechanisms underlying the effects of light on cognitive functions are …
[HTML][HTML] Bright light treatment counteracts stress-induced sleep alterations in mice, via a visual circuit related to the rostromedial tegmental nucleus
L Huang, X Chen, Q Tao, X Wang, X Huang, Y Fu… - PLoS …, 2023 - journals.plos.org
Light in the environment greatly impacts a variety of brain functions, including sleep. Clinical
evidence suggests that bright light treatment has a beneficial effect on stress–related …
evidence suggests that bright light treatment has a beneficial effect on stress–related …
[HTML][HTML] Calretinin neurons in the midline thalamus modulate starvation-induced arousal
R Hua, X Wang, X Chen, X Wang, P Huang, P Li… - Current Biology, 2018 - cell.com
Orchestration of sleep and feeding behavior is essential for organismal health and survival.
Although sleep deprivation promotes feeding and starvation suppresses sleep, the …
Although sleep deprivation promotes feeding and starvation suppresses sleep, the …
[HTML][HTML] The anterior cingulate cortex directly enhances auditory cortical responses in air-puffing-facilitated flight behavior
For survival, animals encode prominent events in complex environments, which modulates
their defense behavior. Here, we design a paradigm that assesses how a mild aversive cue …
their defense behavior. Here, we design a paradigm that assesses how a mild aversive cue …
[HTML][HTML] Anterior cingulate cortex provides the neural substrates for feedback-driven iteration of decision and value representation
Adjusting decision-making under uncertain and dynamic situations is the hallmark of
intelligence. It requires a system capable of converting feedback information to renew the …
intelligence. It requires a system capable of converting feedback information to renew the …
Open-source raspberry Pi-based operant box for translational behavioral testing in rodents
N Buscher, A Ojeda, M Francoeur, S Hulyalkar… - Journal of neuroscience …, 2020 - Elsevier
Background Rodents have been used for decades to probe neural circuits involved in
behavior. Increasingly, attempts have been developed to standardize training paradigms …
behavior. Increasingly, attempts have been developed to standardize training paradigms …
[HTML][HTML] Open source tools for temporally controlled rodent behavior suitable for electrophysiology and optogenetic manipulations
N Solari, K Sviatkó, T Laszlovszky… - Frontiers in systems …, 2018 - frontiersin.org
Understanding how the brain controls behavior requires observing and manipulating neural
activity in awake behaving animals. Neuronal firing is timed at millisecond precision …
activity in awake behaving animals. Neuronal firing is timed at millisecond precision …