Crosstalk between miRNA and PI3K/AKT/mTOR signaling pathway in cancer
M Akbarzadeh, A Mihanfar, S Akbarzadeh, B Yousefi… - Life Sciences, 2021 - Elsevier
Abstract Phosphoinositide-3 kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
signaling pathway is one of the most important proliferative signaling pathways with critical …
signaling pathway is one of the most important proliferative signaling pathways with critical …
Signaling, metabolism, and cancer: An important relationship for therapeutic intervention
In cancerous cells, significant changes occur in the activity of signaling pathways affecting a
wide range of cellular activities ranging from growth and proliferation to apoptosis …
wide range of cellular activities ranging from growth and proliferation to apoptosis …
Identification of modulated MicroRNAs associated with breast cancer, diet, and physical activity
L Falzone, M Grimaldi, E Celentano, LSA Augustin… - Cancers, 2020 - mdpi.com
Simple Summary Healthy diet and physical activity are able to induce beneficial molecular
modifications that have been associated with a lower risk of breast cancer (BC) incidence …
modifications that have been associated with a lower risk of breast cancer (BC) incidence …
Circular RNA Circ_0000442 acts as a sponge of MiR-148b-3p to suppress breast cancer via PTEN/PI3K/Akt signaling pathway
XY Zhang, L Mao - Gene, 2021 - Elsevier
Breast cancer remains the most common malignancy in women worldwide. Circular RNAs
(circRNAs) are a newly validated type of endogenous non-coding RNAs and accumulating …
(circRNAs) are a newly validated type of endogenous non-coding RNAs and accumulating …
Traditional Chinese Medicine for adjuvant treatment of breast cancer: Taohong Siwu Decoction
H Jiang, M Li, K Du, C Ma, Y Cheng, S Wang, X Nie… - Chinese medicine, 2021 - Springer
The high incidence of breast cancer is the greastest threat to women'health all over the
world. Among them, HER-2 positive breast cancer has the characteristics of high …
world. Among them, HER-2 positive breast cancer has the characteristics of high …
The targeting of noncoding RNAs by quercetin in cancer prevention and therapy
M Wang, X Chen, F Yu, L Zhang… - … Medicine and Cellular …, 2022 - Wiley Online Library
The dietary flavonoid quercetin is ubiquitously distributed in fruits, vegetables, and medicinal
herbs. Quercetin has been a focal point in recent years due to its versatile health‐promoting …
herbs. Quercetin has been a focal point in recent years due to its versatile health‐promoting …
Emerging roles and therapeutic interventions of aerobic glycolysis in glioma
W Han, J Shi, J Cao, B Dong, W Guan - OncoTargets and therapy, 2020 - Taylor & Francis
Glioma is the most common type of intracranial malignant tumor, with a great recurrence rate
due to its infiltrative growth, treatment resistance, intra-and intertumoral genetic …
due to its infiltrative growth, treatment resistance, intra-and intertumoral genetic …
Simultaneous and Sensitive Sensing of Intracellular MicroRNA and mRNA for the Detection of the PI3K/AKT Signaling Pathway in Live Cells
D Li, Y Liu, Y Li, Y Xiang, R Yuan - Analytical Chemistry, 2024 - ACS Publications
Simultaneous detection of the concentration variations of microRNA-221 (miRNA-221) and
PTEN mRNA molecules in the PI3K/AKT signaling pathway is of significance to elucidate …
PTEN mRNA molecules in the PI3K/AKT signaling pathway is of significance to elucidate …
Regulators at Every Step—How microRNAs Drive Tumor Cell Invasiveness and Metastasis
Simple Summary Tumor cell invasiveness and metastasis are key processes in cancer
progression and are composed of many steps. All of them are regulated by multiple …
progression and are composed of many steps. All of them are regulated by multiple …
Discovery of anti-hepatoma agents from 1, 4, 5, 6, 7, 8-hexahydropyrido [4, 3-d] pyrimidine by inhibiting PI3K/AKT/NF-κB pathway activation
YQ Zhou, Y Sun, HL Luo, ZF Gao, HQ Zhang… - European Journal of …, 2021 - Elsevier
In order to obtain new anti-hepatoma drugs with low toxicity, some 1, 4, 5, 6, 7, 8-
hexahydropyrido [4, 3-d] pyrimidines (PPMs, 4a-t) were synthesized in this study. Many of …
hexahydropyrido [4, 3-d] pyrimidines (PPMs, 4a-t) were synthesized in this study. Many of …