Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations
AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are episodes of
symptom worsening 1 that have significant adverse consequences for patients. 2 The …
symptom worsening 1 that have significant adverse consequences for patients. 2 The …
Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
[HTML][HTML] COVID-19 and COPD: a narrative review of the basic science and clinical outcomes
The 2019 coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in …
syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in …
The role of the microbiome in exacerbations of chronic lung diseases
Culture-independent microbiological techniques have shown a previously unappreciated
complexity to the bacterial microbiome of the respiratory tract that forces reconsideration of …
complexity to the bacterial microbiome of the respiratory tract that forces reconsideration of …
Systemic manifestations and comorbidities of COPD
Increasing evidence indicates that chronic obstructive pulmonary disease (COPD) is a
complex disease involving more than airflow obstruction. Airflow obstruction has profound …
complex disease involving more than airflow obstruction. Airflow obstruction has profound …
COPD–do the right thing
H Sandelowsky, UM Weinreich, BB Aarli, J Sundh… - BMC family …, 2021 - Springer
A gap exists between guidelines and real-world clinical practice for the management and
treatment of chronic obstructive pulmonary disease (COPD). Although this has narrowed in …
treatment of chronic obstructive pulmonary disease (COPD). Although this has narrowed in …
Infection in the pathogenesis and course of chronic obstructive pulmonary disease
New molecular, cellular, and immunologic techniques used to study host–pathogen
interactions have led to a reexamination of the role of infection in chronic obstructive …
interactions have led to a reexamination of the role of infection in chronic obstructive …
COPD exacerbations: defining their cause and prevention
JA Wedzicha, TAR Seemungal - The lancet, 2007 - thelancet.com
Exacerbations of chronic obstructive pulmonary disease (COPD) are episodes of worsening
of symptoms, leading to substantial morbidity and mortality. COPD exacerbations are …
of symptoms, leading to substantial morbidity and mortality. COPD exacerbations are …
Microbiome dysbiosis in lung cancer: from composition to therapy
NN Liu, Q Ma, Y Ge, CX Yi, LQ Wei, JC Tan… - NPJ precision …, 2020 - nature.com
The correlations between microbiota dysbiosis and cancer have gained extensive attention
and been widely explored. As a leading cancer diagnosis worldwide, lung cancer poses a …
and been widely explored. As a leading cancer diagnosis worldwide, lung cancer poses a …
The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide
JA Wedzicha, PMA Calverley… - American journal of …, 2008 - atsjournals.org
Rationale: Exacerbations are key drivers of morbidity and mortality in chronic obstructive
pulmonary disease (COPD). Objectives: We compared the relative efficacy of the long-acting …
pulmonary disease (COPD). Objectives: We compared the relative efficacy of the long-acting …