DNA replication: Mechanisms and therapeutic interventions for diseases
HY Song, R Shen, H Mahasin, YN Guo, DG Wang - MedComm, 2023 - Wiley Online Library
Accurate and integral cellular DNA replication is modulated by multiple replication‐
associated proteins, which is fundamental to preserve genome stability. Furthermore …
associated proteins, which is fundamental to preserve genome stability. Furthermore …
DNA replication licensing proteins: Saints and sinners in cancer
DNA replication is all-or-none process in the cell, meaning, once the DNA replication begins
it proceeds to completion. Hence, to achieve maximum control of DNA replication, eukaryotic …
it proceeds to completion. Hence, to achieve maximum control of DNA replication, eukaryotic …
CDT1 is a novel prognostic and predictive biomarkers for hepatocellular carcinoma
C Cai, Y Zhang, X Hu, W Hu, S Yang, H Qiu… - Frontiers in …, 2021 - frontiersin.org
Objective Hepatocellular carcinoma (HCC) is one of the most common malignant tumors
endangering human health and life in the 21st century. Chromatin licensing and DNA …
endangering human health and life in the 21st century. Chromatin licensing and DNA …
MCM10, a potential diagnostic, immunological, and prognostic biomarker in pan-cancer
D Chen, N Zhong, Z Guo, Q Ji, Z Dong, J Zheng… - Scientific Reports, 2023 - nature.com
Microchromosome maintenance (MCM) proteins are a number of nuclear proteins with
significant roles in the development of cancer by influencing the process of cellular DNA …
significant roles in the development of cancer by influencing the process of cellular DNA …
[HTML][HTML] NUSAP1 promotes the metastasis of breast cancer cells via the AMPK/PPARγ signaling pathway
J Qiu, L Xu, X Zeng, Z Wu, Y Wang… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background The biological function and molecular mechanism of nucleolar spindle-
associated protein 1 (NUSAP1) in breast cancer remain controversial, this study aimed to …
associated protein 1 (NUSAP1) in breast cancer remain controversial, this study aimed to …
MCM10 compensates for Myc‐induced DNA replication stress in breast cancer stem‐like cells
T Murayama, Y Takeuchi, K Yamawaki… - Cancer …, 2021 - Wiley Online Library
Cancer stem‐like cells (CSCs) induce drug resistance and recurrence of tumors when they
experience DNA replication stress. However, the mechanisms underlying DNA replication …
experience DNA replication stress. However, the mechanisms underlying DNA replication …
MCM10 facilitates the invaded/migrated potentials of breast cancer cells via Wnt/β‐catenin signaling and is positively interlinked with poor prognosis in breast …
WD Yang, L Wang - Journal of Biochemical and Molecular …, 2019 - Wiley Online Library
The minichromosome maintenance protein 10 (MCM10) is one of the MCM proteins that
initiate DNA replication by interacting with CDC45‐MCM2–7. It has been reported that …
initiate DNA replication by interacting with CDC45‐MCM2–7. It has been reported that …
Co-expression network analysis identified candidate biomarkers in association with progression and prognosis of breast cancer
Q Zhou, J Ren, J Hou, G Wang, L Ju, Y Xiao… - Journal of Cancer …, 2019 - Springer
Purpose Breast cancer is one of the most common malignancies among females, and its
prognosis is affected by a complex network of gene interactions. Weighted gene co …
prognosis is affected by a complex network of gene interactions. Weighted gene co …
Gene-level germline contributions to clinical risk of recurrence scores in Black and White patients with breast cancer
Continuous risk of recurrence scores (CRS) based on tumor gene expression are vital
prognostic tools for breast cancer. Studies have shown that Black women (BW) have higher …
prognostic tools for breast cancer. Studies have shown that Black women (BW) have higher …
Aberrant MCM10 SUMOylation induces genomic instability mediated by a genetic variant associated with survival of esophageal squamous cell carcinoma
J Tian, Z Lu, S Niu, S Zhang, P Ying… - Clinical and …, 2021 - Wiley Online Library
Background Esophageal squamous cell carcinoma (ESCC) is one of the common
gastrointestinal malignancy with an inferior prognosis outcome. DNA replication licensing …
gastrointestinal malignancy with an inferior prognosis outcome. DNA replication licensing …